Liver function test abnormal: Which Medications Cause It? (15,052 Reports Across 727 Drugs)
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Liver function test abnormal has been reported as an adverse event with 727 different drugs in the FDA's FAERS database, with 15,052 total reports. 1,063 of these reports resulted in death.The drugs most commonly associated with Liver function test abnormal are METHOTREXATE, ETANERCEPT, and ADALIMUMAB.
15,052
Total Reports
727
Drugs Involved
1,063
Deaths
5,665
Hospitalizations
55.4 yrs
Average Patient Age
60.5% / 39.5%
Female / Male
Which Drugs Cause Liver function test abnormal Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 1,416 | 0.6% | 39 | 313 | 102 |
| ETANERCEPT | 1,013 | 0.3% | 22 | 159 | 192 |
| ADALIMUMAB | 879 | 0.2% | 5 | 228 | 69 |
| INFLIXIMAB | 609 | 0.4% | 6 | 100 | 187 |
| ATORVASTATIN | 579 | 0.7% | 8 | 337 | 38 |
| TOCILIZUMAB | 526 | 0.5% | 5 | 105 | 77 |
| LEFLUNOMIDE | 489 | 0.9% | 17 | 78 | 18 |
| ACETAMINOPHEN | 465 | 0.3% | 49 | 283 | 49 |
| TOFACITINIB | 436 | 0.3% | 6 | 66 | 33 |
| ABATACEPT | 431 | 0.4% | 2 | 109 | 64 |
| HYDROXYCHLOROQUINE | 429 | 0.6% | 0 | 111 | 66 |
| SULFASALAZINE | 429 | 1.1% | 2 | 119 | 182 |
| RITUXIMAB | 355 | 0.2% | 28 | 83 | 10 |
| TACROLIMUS | 288 | 0.3% | 29 | 92 | 136 |
| MYCOPHENOLATE MOFETIL | 265 | 0.4% | 20 | 75 | 107 |
| PREDNISONE | 261 | 0.2% | 29 | 161 | 85 |
| CYCLOSPORINE | 260 | 0.4% | 7 | 43 | 134 |
| AMBRISENTAN | 254 | 0.3% | 9 | 20 | 1 |
| SIMVASTATIN | 223 | 0.8% | 31 | 167 | 26 |
| FINGOLIMOD | 215 | 0.3% | 0 | 33 | 4 |