Liver function test increased: Which Medications Cause It? (19,587 Reports Across 948 Drugs)
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Liver function test increased has been reported as an adverse event with 948 different drugs in the FDA's FAERS database, with 19,587 total reports. 1,715 of these reports resulted in death.The drugs most commonly associated with Liver function test increased are METHOTREXATE, ADALIMUMAB, and ETANERCEPT.
19,587
Total Reports
948
Drugs Involved
1,715
Deaths
5,708
Hospitalizations
54.2 yrs
Average Patient Age
65.0% / 35.0%
Female / Male
Which Drugs Cause Liver function test increased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 3,839 | 1.5% | 714 | 964 | 608 |
| ADALIMUMAB | 2,070 | 0.4% | 672 | 861 | 589 |
| ETANERCEPT | 1,829 | 0.5% | 453 | 583 | 425 |
| LEFLUNOMIDE | 1,521 | 2.7% | 614 | 695 | 580 |
| ABATACEPT | 1,415 | 1.2% | 554 | 618 | 489 |
| TOCILIZUMAB | 1,406 | 1.4% | 631 | 698 | 478 |
| RITUXIMAB | 1,325 | 0.7% | 673 | 803 | 599 |
| SULFASALAZINE | 1,263 | 3.1% | 559 | 580 | 464 |
| HYDROXYCHLOROQUINE | 1,259 | 1.9% | 533 | 587 | 445 |
| TOFACITINIB | 1,221 | 0.8% | 473 | 462 | 375 |
| INFLIXIMAB | 1,191 | 0.9% | 534 | 564 | 430 |
| SECUKINUMAB | 1,027 | 0.7% | 661 | 711 | 620 |
| CERTOLIZUMAB PEGOL | 966 | 1.0% | 549 | 585 | 452 |
| GOLIMUMAB | 936 | 1.4% | 531 | 566 | 457 |
| ACETAMINOPHEN | 891 | 0.7% | 533 | 724 | 490 |
| PREDNISONE | 876 | 0.6% | 553 | 609 | 481 |
| AZATHIOPRINE | 820 | 2.5% | 549 | 516 | 429 |
| DICLOFENAC | 804 | 0.9% | 705 | 613 | 588 |
| USTEKINUMAB | 724 | 0.9% | 456 | 455 | 392 |
| APREMILAST | 707 | 0.5% | 531 | 468 | 403 |