Lupus nephritis: Which Medications Cause It? (1,420 Reports Across 102 Drugs)
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Lupus nephritis has been reported as an adverse event with 102 different drugs in the FDA's FAERS database, with 1,420 total reports. 42 of these reports resulted in death.The drugs most commonly associated with Lupus nephritis are BELIMUMAB, MYCOPHENOLATE MOFETIL, and RITUXIMAB.
1,420
Total Reports
102
Drugs Involved
42
Deaths
519
Hospitalizations
38.0 yrs
Average Patient Age
78.0% / 22.0%
Female / Male
Which Drugs Cause Lupus nephritis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BELIMUMAB | 314 | 1.2% | 2 | 63 | 4 |
| MYCOPHENOLATE MOFETIL | 286 | 0.4% | 5 | 88 | 10 |
| RITUXIMAB | 241 | 0.1% | 3 | 111 | 15 |
| HYDROXYCHLOROQUINE | 230 | 0.3% | 0 | 104 | 9 |
| PREDNISONE | 188 | 0.1% | 3 | 101 | 5 |
| METHOTREXATE | 173 | 0.1% | 1 | 90 | 4 |
| PREDNISOLONE | 167 | 0.2% | 5 | 39 | 9 |
| CYCLOPHOSPHAMIDE | 151 | 0.1% | 1 | 44 | 12 |
| AZATHIOPRINE | 147 | 0.4% | 0 | 36 | 8 |
| HYDRALAZINE | 135 | 2.3% | 4 | 58 | 5 |
| METHYLPREDNISOLONE | 131 | 0.2% | 1 | 94 | 10 |
| TACROLIMUS | 123 | 0.1% | 5 | 45 | 4 |
| AMLODIPINE | 85 | 0.1% | 0 | 61 | 1 |
| MYCOPHENOLATE | 85 | 1.1% | 0 | 56 | 4 |
| CYCLOSPORINE | 82 | 0.1% | 1 | 14 | 2 |
| FOLIC ACID | 77 | 0.3% | 0 | 53 | 1 |
| PANTOPRAZOLE | 66 | 0.1% | 1 | 3 | 1 |
| APIXABAN | 64 | 0.0% | 0 | 59 | 0 |
| MYCOPHENOLIC ACID | 62 | 0.4% | 0 | 18 | 2 |
| LEFLUNOMIDE | 61 | 0.1% | 0 | 55 | 0 |