Macular hole: Which Medications Cause It? (966 Reports Across 50 Drugs)
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Macular hole has been reported as an adverse event with 50 different drugs in the FDA's FAERS database, with 966 total reports. 4 of these reports resulted in death.The drugs most commonly associated with Macular hole are AFLIBERCEPT, ADALIMUMAB, and RANIBIZUMAB.
966
Total Reports
50
Drugs Involved
4
Deaths
138
Hospitalizations
64.8 yrs
Average Patient Age
69.4% / 30.6%
Female / Male
Which Drugs Cause Macular hole Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| AFLIBERCEPT | 131 | 0.5% | 1 | 16 | 0 |
| ADALIMUMAB | 86 | 0.0% | 0 | 12 | 0 |
| RANIBIZUMAB | 81 | 0.5% | 0 | 16 | 0 |
| BEVACIZUMAB | 40 | 0.1% | 0 | 5 | 0 |
| OCRIPLASMIN | 38 | 12.4% | 0 | 0 | 0 |
| ALTEPLASE | 18 | 0.1% | 0 | 0 | 0 |
| FINGOLIMOD | 17 | 0.0% | 0 | 2 | 0 |
| LATANOPROST | 17 | 0.1% | 0 | 2 | 0 |
| DEXAMETHASONE | 16 | 0.0% | 0 | 2 | 0 |
| ETANERCEPT | 15 | 0.0% | 0 | 3 | 1 |
| TAMSULOSIN | 14 | 0.1% | 0 | 0 | 1 |
| UPADACITINIB | 14 | 0.0% | 0 | 2 | 0 |
| OMEPRAZOLE | 13 | 0.0% | 0 | 0 | 1 |
| FINASTERIDE | 12 | 0.1% | 0 | 0 | 0 |
| TAMOXIFEN | 12 | 0.1% | 0 | 5 | 0 |
| INTERFERON BETA-1A | 11 | 0.0% | 0 | 1 | 0 |
| METHOTREXATE | 11 | 0.0% | 0 | 1 | 0 |
| PENTOSAN POLYSULFATE | 11 | 0.3% | 0 | 0 | 0 |
| SEMAGLUTIDE | 11 | 0.0% | 0 | 0 | 0 |
| HYDROXYCHLOROQUINE | 10 | 0.0% | 0 | 0 | 0 |