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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Macule: Which Medications Cause It? (2,427 Reports Across 187 Drugs)

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Macule has been reported as an adverse event with 187 different drugs in the FDA's FAERS database, with 2,427 total reports. 61 of these reports resulted in death.The drugs most commonly associated with Macule are SECUKINUMAB, ETANERCEPT, and METHOTREXATE.

2,427
Total Reports
187
Drugs Involved
61
Deaths
506
Hospitalizations
53.6 yrs
Average Patient Age
59.1% / 40.9%
Female / Male

Which Drugs Cause Macule Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
SECUKINUMAB 747 0.5% 3 39 9
ETANERCEPT 165 0.1% 1 5 1
METHOTREXATE 119 0.1% 1 15 4
CLOBETASOL 93 1.2% 0 1 0
TRIAMCINOLONE 56 0.8% 0 0 0
AMOXICILLIN 40 0.1% 2 26 2
LAMOTRIGINE 39 0.1% 0 30 10
OMEPRAZOLE 38 0.0% 0 7 1
DENOSUMAB 36 0.0% 1 1 0
IBUPROFEN 36 0.0% 0 17 1
PANTOPRAZOLE 35 0.0% 4 8 5
APREMILAST 34 0.0% 0 1 1
LENALIDOMIDE 34 0.0% 0 6 0
ADALIMUMAB 32 0.0% 0 4 0
ATORVASTATIN 32 0.0% 1 11 0
ABATACEPT 31 0.0% 0 6 1
APIXABAN 31 0.0% 0 8 0
CARBAMAZEPINE 31 0.1% 1 19 3
PREDNISONE 29 0.0% 6 11 5
TACROLIMUS 29 0.0% 2 1 1

View all 187 drugs →

Top 3 Drugs Associated With Macule

747 reports
165 reports
119 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)