Maternal exposure before pregnancy: Which Medications Cause It? (5,822 Reports Across 239 Drugs)
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Maternal exposure before pregnancy has been reported as an adverse event with 239 different drugs in the FDA's FAERS database, with 5,822 total reports. 93 of these reports resulted in death.The drugs most commonly associated with Maternal exposure before pregnancy are CERTOLIZUMAB PEGOL, LEVONORGESTREL, and OCRELIZUMAB.
5,822
Total Reports
239
Drugs Involved
93
Deaths
937
Hospitalizations
30.8 yrs
Average Patient Age
95.6% / 4.4%
Female / Male
Which Drugs Cause Maternal exposure before pregnancy Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CERTOLIZUMAB PEGOL | 1,680 | 1.7% | 22 | 272 | 11 |
| LEVONORGESTREL | 557 | 0.5% | 0 | 32 | 8 |
| OCRELIZUMAB | 434 | 0.8% | 2 | 72 | 5 |
| METHOTREXATE | 267 | 0.1% | 9 | 19 | 8 |
| ETHINYL ESTRADIOL\ETONOGESTREL | 257 | 2.2% | 0 | 184 | 4 |
| LEVETIRACETAM | 256 | 0.4% | 11 | 47 | 3 |
| CYCLOPHOSPHAMIDE | 221 | 0.2% | 30 | 3 | 1 |
| FINGOLIMOD | 180 | 0.3% | 2 | 9 | 0 |
| LACOSAMIDE | 154 | 0.7% | 3 | 20 | 2 |
| RITUXIMAB | 133 | 0.1% | 7 | 19 | 7 |
| ISOTRETINOIN | 112 | 0.3% | 0 | 0 | 0 |
| VINCRISTINE | 101 | 0.1% | 1 | 2 | 1 |
| ETOPOSIDE | 100 | 0.2% | 1 | 0 | 0 |
| DACTINOMYCIN | 99 | 3.5% | 1 | 0 | 0 |
| OMALIZUMAB | 98 | 0.2% | 0 | 20 | 8 |
| PREDNISONE | 97 | 0.1% | 6 | 23 | 6 |
| ETONOGESTREL | 96 | 0.2% | 1 | 4 | 0 |
| INFLIXIMAB | 96 | 0.1% | 7 | 22 | 8 |
| FOLIC ACID | 83 | 0.4% | 6 | 25 | 6 |
| CLADRIBINE | 74 | 1.0% | 0 | 7 | 0 |