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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Mental impairment: Which Medications Cause It? (16,880 Reports Across 630 Drugs)

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Mental impairment has been reported as an adverse event with 630 different drugs in the FDA's FAERS database, with 16,880 total reports. 633 of these reports resulted in death.The drugs most commonly associated with Mental impairment are CLOZAPINE, OXYCODONE, and ARIPIPRAZOLE.

16,880
Total Reports
630
Drugs Involved
633
Deaths
4,729
Hospitalizations
52.7 yrs
Average Patient Age
60.2% / 39.8%
Female / Male

Which Drugs Cause Mental impairment Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
CLOZAPINE 1,691 1.8% 44 1,308 51
OXYCODONE 720 0.4% 97 174 23
ARIPIPRAZOLE 563 0.9% 8 220 17
OLANZAPINE 556 1.1% 11 235 30
PREGABALIN 497 0.5% 24 100 19
QUETIAPINE 443 0.6% 17 196 39
DIMETHYL 388 0.4% 1 52 2
ACETAMINOPHEN\HYDROCODONE 382 0.4% 55 85 8
RISPERIDONE 381 0.5% 13 138 14
ACETAMINOPHEN\OXYCODONE 377 0.4% 57 94 9
NATALIZUMAB 351 0.6% 0 64 3
MORPHINE 347 0.3% 35 108 19
GABAPENTIN 345 0.5% 5 108 36
HYDROMORPHONE 332 0.4% 47 119 7
DULOXETINE 304 0.6% 1 33 9
INTERFERON BETA-1A 284 0.4% 0 50 2
SERTRALINE 283 0.5% 17 107 8
TRAMADOL 280 0.4% 21 62 10
CLONAZEPAM 260 0.7% 16 104 20
ADALIMUMAB 231 0.1% 7 87 9

View all 630 drugs →

Top 3 Drugs Associated With Mental impairment

1,691 reports
720 reports
563 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)