Mixed liver injury: Which Medications Cause It? (2,312 Reports Across 294 Drugs)
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Mixed liver injury has been reported as an adverse event with 294 different drugs in the FDA's FAERS database, with 2,312 total reports. 102 of these reports resulted in death.The drugs most commonly associated with Mixed liver injury are ATORVASTATIN, ACETAMINOPHEN, and AMOXICILLIN\CLAVULANATE.
2,312
Total Reports
294
Drugs Involved
102
Deaths
1,219
Hospitalizations
62.8 yrs
Average Patient Age
57.4% / 42.6%
Female / Male
Which Drugs Cause Mixed liver injury Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ATORVASTATIN | 342 | 0.4% | 8 | 234 | 1 |
| ACETAMINOPHEN | 331 | 0.2% | 18 | 203 | 11 |
| AMOXICILLIN\CLAVULANATE | 183 | 1.2% | 4 | 74 | 0 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 171 | 0.4% | 26 | 91 | 0 |
| ENOXAPARIN | 119 | 0.5% | 22 | 61 | 0 |
| AMOXICILLIN | 101 | 0.3% | 7 | 62 | 6 |
| AMOXICILLIN\CLAVULANIC ACID | 87 | 0.8% | 4 | 33 | 3 |
| PIPERACILLIN\TAZOBACTAM | 86 | 0.5% | 1 | 36 | 0 |
| PEMBROLIZUMAB | 81 | 0.1% | 10 | 42 | 12 |
| LEVOFLOXACIN | 80 | 0.2% | 1 | 46 | 0 |
| VALACYCLOVIR | 75 | 0.6% | 21 | 43 | 0 |
| APIXABAN | 73 | 0.1% | 15 | 57 | 0 |
| PANTOPRAZOLE | 72 | 0.1% | 2 | 36 | 1 |
| FUROSEMIDE | 70 | 0.1% | 21 | 40 | 0 |
| LANSOPRAZOLE | 69 | 0.1% | 0 | 41 | 0 |
| ESOMEPRAZOLE | 62 | 0.1% | 0 | 38 | 0 |
| CARBOPLATIN | 57 | 0.1% | 1 | 29 | 2 |
| SERTRALINE | 57 | 0.1% | 3 | 37 | 0 |
| MEROPENEM | 56 | 0.4% | 20 | 16 | 1 |
| TRAMADOL | 55 | 0.1% | 0 | 34 | 9 |