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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Multi-organ failure: Which Medications Cause It? (3,716 Reports Across 334 Drugs)

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Multi-organ failure has been reported as an adverse event with 334 different drugs in the FDA's FAERS database, with 3,716 total reports. 3,175 of these reports resulted in death.The drugs most commonly associated with Multi-organ failure are CYCLOPHOSPHAMIDE, METHOTREXATE, and CYTARABINE.

3,716
Total Reports
334
Drugs Involved
3,175
Deaths
2,070
Hospitalizations
55.8 yrs
Average Patient Age
48.8% / 51.2%
Female / Male

Which Drugs Cause Multi-organ failure Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
CYCLOPHOSPHAMIDE 151 0.1% 136 66 15
METHOTREXATE 130 0.1% 112 73 15
CYTARABINE 117 0.3% 96 56 13
METFORMIN 115 0.1% 83 82 32
PREDNISONE 106 0.1% 89 58 15
DOXORUBICIN 104 0.1% 94 52 6
DEXAMETHASONE 103 0.1% 85 60 12
CYCLOSPORINE 99 0.1% 84 39 6
VINCRISTINE 98 0.1% 84 45 6
PREDNISOLONE 96 0.1% 91 50 9
RIBAVIRIN 88 0.2% 83 57 12
RITUXIMAB 88 0.1% 76 49 11
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM 79 0.1% 75 49 0
TACROLIMUS 78 0.1% 71 34 6
FLUDARABINE 75 0.3% 72 20 4
MYCOPHENOLATE MOFETIL 75 0.1% 66 30 5
ACETAMINOPHEN 69 0.1% 53 45 13
DABIGATRAN ETEXILATE 69 0.2% 66 49 13
VANCOMYCIN 67 0.2% 50 37 16
ETOPOSIDE 64 0.1% 52 31 5

View all 334 drugs →

Top 3 Drugs Associated With Multi-organ failure

151 reports
130 reports
117 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)