Multiple congenital abnormalities: Which Medications Cause It? (754 Reports Across 84 Drugs)
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Multiple congenital abnormalities has been reported as an adverse event with 84 different drugs in the FDA's FAERS database, with 754 total reports. 168 of these reports resulted in death.The drugs most commonly associated with Multiple congenital abnormalities are OXYCODONE, ACETAMINOPHEN\HYDROCODONE, and ACETAMINOPHEN\OXYCODONE.
754
Total Reports
84
Drugs Involved
168
Deaths
78
Hospitalizations
20.2 yrs
Average Patient Age
43.8% / 56.2%
Female / Male
Which Drugs Cause Multiple congenital abnormalities Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXYCODONE | 173 | 0.1% | 14 | 11 | 1 |
| ACETAMINOPHEN\HYDROCODONE | 107 | 0.1% | 11 | 9 | 1 |
| ACETAMINOPHEN\OXYCODONE | 102 | 0.1% | 7 | 8 | 1 |
| ONDANSETRON | 96 | 0.4% | 7 | 17 | 2 |
| HYDROMORPHONE | 95 | 0.1% | 8 | 4 | 1 |
| MORPHINE | 88 | 0.1% | 7 | 4 | 1 |
| TRAMADOL | 68 | 0.1% | 12 | 3 | 1 |
| VALPROATE | 59 | 0.4% | 9 | 14 | 0 |
| BUPRENORPHINE | 58 | 0.1% | 3 | 4 | 1 |
| LAMOTRIGINE | 45 | 0.1% | 14 | 3 | 0 |
| HYDROCODONE | 37 | 0.1% | 3 | 2 | 1 |
| VALPROIC ACID | 33 | 0.2% | 4 | 3 | 1 |
| LEVETIRACETAM | 30 | 0.1% | 10 | 0 | 0 |
| METFORMIN | 29 | 0.0% | 12 | 0 | 0 |
| ASPIRIN | 25 | 0.0% | 23 | 0 | 0 |
| FOLIC ACID | 24 | 0.1% | 3 | 1 | 0 |
| OMEPRAZOLE | 24 | 0.0% | 2 | 0 | 0 |
| PREDNISONE | 24 | 0.0% | 16 | 2 | 0 |
| MYCOPHENOLATE MOFETIL | 21 | 0.0% | 11 | 5 | 4 |
| ACETAMINOPHEN\OXYCODONE\OXYCODONE TEREPHTHALATE | 19 | 0.2% | 2 | 3 | 0 |