Muscle spasticity: Which Medications Cause It? (8,549 Reports Across 422 Drugs)
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Muscle spasticity has been reported as an adverse event with 422 different drugs in the FDA's FAERS database, with 8,549 total reports. 284 of these reports resulted in death.The drugs most commonly associated with Muscle spasticity are BACLOFEN, METHOTREXATE, and ACETAMINOPHEN.
8,549
Total Reports
422
Drugs Involved
284
Deaths
2,770
Hospitalizations
46.8 yrs
Average Patient Age
65.7% / 34.3%
Female / Male
Which Drugs Cause Muscle spasticity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BACLOFEN | 2,893 | 11.2% | 50 | 872 | 93 |
| METHOTREXATE | 829 | 0.3% | 111 | 282 | 270 |
| ACETAMINOPHEN | 745 | 0.5% | 85 | 292 | 259 |
| TOCILIZUMAB | 646 | 0.7% | 90 | 111 | 93 |
| ABATACEPT | 628 | 0.5% | 77 | 97 | 95 |
| LEFLUNOMIDE | 617 | 1.1% | 80 | 93 | 93 |
| OCRELIZUMAB | 610 | 1.1% | 4 | 251 | 0 |
| CERTOLIZUMAB PEGOL | 607 | 0.6% | 76 | 88 | 88 |
| GOLIMUMAB | 607 | 0.9% | 76 | 88 | 88 |
| ETANERCEPT | 606 | 0.2% | 75 | 87 | 85 |
| CHLORHEXIDINE | 566 | 6.3% | 77 | 90 | 90 |
| DALFAMPRIDINE | 566 | 1.0% | 2 | 107 | 1 |
| FINGOLIMOD | 515 | 0.7% | 9 | 143 | 15 |
| OXYCODONE | 461 | 0.2% | 33 | 72 | 46 |
| OXYCODONE TEREPHTHALATE | 390 | 8.5% | 32 | 42 | 42 |
| AMLODIPINE | 385 | 0.6% | 5 | 281 | 235 |
| DIMETHYL | 381 | 0.4% | 4 | 79 | 1 |
| TERIFLUNOMIDE | 361 | 0.9% | 2 | 55 | 2 |
| RITUXIMAB | 359 | 0.2% | 125 | 294 | 256 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 336 | 0.9% | 33 | 52 | 46 |