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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Muscle tightness: Which Medications Cause It? (11,343 Reports Across 531 Drugs)

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Muscle tightness has been reported as an adverse event with 531 different drugs in the FDA's FAERS database, with 11,343 total reports. 111 of these reports resulted in death.The drugs most commonly associated with Muscle tightness are BACLOFEN, ADALIMUMAB, and CIPROFLOXACIN.

11,343
Total Reports
531
Drugs Involved
111
Deaths
1,957
Hospitalizations
51.6 yrs
Average Patient Age
68.0% / 32.0%
Female / Male

Which Drugs Cause Muscle tightness Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
BACLOFEN 391 1.5% 5 120 11
ADALIMUMAB 321 0.1% 0 78 2
CIPROFLOXACIN 269 0.6% 1 69 10
DIMETHYL 206 0.2% 0 42 2
FINGOLIMOD 183 0.3% 0 17 0
ETANERCEPT 178 0.1% 0 21 0
SERTRALINE 175 0.3% 15 22 11
LEVOFLOXACIN 171 0.4% 1 45 7
ONABOTULINUMTOXINA 168 0.3% 1 12 1
OCRELIZUMAB 167 0.3% 0 42 1
DUPILUMAB 163 0.0% 0 10 0
EVOLOCUMAB 162 0.1% 0 3 0
LENALIDOMIDE 161 0.1% 0 9 0
DALFAMPRIDINE 155 0.3% 0 18 1
SODIUM OXYBATE 154 0.3% 0 9 1
TERIPARATIDE 151 0.2% 0 5 0
PREGABALIN 150 0.2% 13 23 7
DULOXETINE 147 0.3% 0 31 1
INTERFERON BETA-1A 144 0.2% 1 43 0
ATORVASTATIN 143 0.2% 2 19 3

View all 531 drugs →

Top 3 Drugs Associated With Muscle tightness

391 reports
321 reports
269 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)