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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Musculoskeletal pain: Which Medications Cause It? (37,156 Reports Across 1,015 Drugs)

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Musculoskeletal pain has been reported as an adverse event with 1,015 different drugs in the FDA's FAERS database, with 37,156 total reports. 2,459 of these reports resulted in death.The drugs most commonly associated with Musculoskeletal pain are ETANERCEPT, ADALIMUMAB, and METHOTREXATE.

37,156
Total Reports
1,015
Drugs Involved
2,459
Deaths
10,215
Hospitalizations
58.8 yrs
Average Patient Age
70.3% / 29.7%
Female / Male

Which Drugs Cause Musculoskeletal pain Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ETANERCEPT 5,000 1.4% 743 1,344 845
ADALIMUMAB 4,742 1.0% 1,053 1,972 1,125
METHOTREXATE 3,981 1.6% 1,091 1,704 1,186
ABATACEPT 2,868 2.5% 916 1,365 1,049
TOCILIZUMAB 2,751 2.8% 1,026 1,446 983
RITUXIMAB 2,674 1.5% 1,154 1,548 1,137
HYDROXYCHLOROQUINE 2,455 3.7% 970 1,218 1,000
LEFLUNOMIDE 2,453 4.3% 1,033 1,337 1,093
TOFACITINIB 2,427 1.6% 871 1,159 922
SULFASALAZINE 2,201 5.5% 948 1,202 979
INFLIXIMAB 2,059 1.5% 945 1,198 1,012
SECUKINUMAB 1,913 1.3% 1,107 1,249 1,152
PREDNISONE 1,905 1.2% 1,009 1,305 1,063
GOLIMUMAB 1,687 2.4% 913 1,101 972
CERTOLIZUMAB PEGOL 1,685 1.7% 898 1,071 931
DICLOFENAC 1,633 1.9% 1,125 1,223 1,168
ALENDRONATE 1,504 5.4% 988 1,182 1,022
FOLIC ACID 1,269 5.6% 936 1,055 997
ACETAMINOPHEN 1,231 0.9% 849 948 939
NAPROXEN 1,231 2.3% 774 884 752

View all 1,015 drugs →

Top 3 Drugs Associated With Musculoskeletal pain

5,000 reports
4,742 reports
3,981 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)