Myasthenia gravis crisis: Which Medications Cause It? (1,204 Reports Across 67 Drugs)
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Myasthenia gravis crisis has been reported as an adverse event with 67 different drugs in the FDA's FAERS database, with 1,204 total reports. 90 of these reports resulted in death.The drugs most commonly associated with Myasthenia gravis crisis are EFGARTIGIMOD ALFA-FCAB, ECULIZUMAB, and RAVULIZUMAB-CWVZ.
1,204
Total Reports
67
Drugs Involved
90
Deaths
907
Hospitalizations
59.6 yrs
Average Patient Age
55.1% / 44.9%
Female / Male
Which Drugs Cause Myasthenia gravis crisis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| EFGARTIGIMOD ALFA-FCAB | 400 | 12.1% | 30 | 349 | 81 |
| ECULIZUMAB | 183 | 0.4% | 13 | 121 | 13 |
| RAVULIZUMAB-CWVZ | 89 | 0.9% | 1 | 60 | 5 |
| PREDNISONE | 57 | 0.0% | 2 | 41 | 14 |
| PYRIDOSTIGMINE | 55 | 2.8% | 3 | 38 | 14 |
| RITUXIMAB | 41 | 0.0% | 7 | 21 | 5 |
| HUMAN IMMUNOGLOBULIN G | 35 | 0.1% | 1 | 24 | 7 |
| AZATHIOPRINE | 33 | 0.1% | 4 | 18 | 11 |
| MYCOPHENOLATE MOFETIL | 33 | 0.0% | 0 | 20 | 4 |
| PEMBROLIZUMAB | 31 | 0.0% | 9 | 23 | 11 |
| LEVOFLOXACIN | 30 | 0.1% | 0 | 23 | 23 |
| NIVOLUMAB | 30 | 0.0% | 7 | 24 | 21 |
| PREDNISOLONE | 30 | 0.0% | 8 | 19 | 6 |
| ATORVASTATIN | 26 | 0.0% | 8 | 21 | 5 |
| EFGARTIGIMOD ALFA | 25 | 10.0% | 0 | 16 | 9 |
| EFGARTIGIMOD ALFA\HYALURONIDASE-QVFC | 24 | 6.0% | 0 | 16 | 7 |
| AZITHROMYCIN ANHYDROUS | 22 | 0.2% | 0 | 16 | 13 |
| VANCOMYCIN | 22 | 0.1% | 0 | 19 | 7 |
| DOXORUBICIN | 20 | 0.0% | 0 | 12 | 13 |
| CISPLATIN | 19 | 0.0% | 0 | 11 | 13 |