Myoclonus: Which Medications Cause It? (7,700 Reports Across 458 Drugs)
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Myoclonus has been reported as an adverse event with 458 different drugs in the FDA's FAERS database, with 7,700 total reports. 382 of these reports resulted in death.The drugs most commonly associated with Myoclonus are GABAPENTIN, QUETIAPINE, and LEVETIRACETAM.
7,700
Total Reports
458
Drugs Involved
382
Deaths
4,179
Hospitalizations
53.8 yrs
Average Patient Age
52.2% / 47.8%
Female / Male
Which Drugs Cause Myoclonus Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| GABAPENTIN | 809 | 1.1% | 23 | 483 | 43 |
| QUETIAPINE | 367 | 0.5% | 17 | 255 | 46 |
| LEVETIRACETAM | 358 | 0.6% | 7 | 131 | 30 |
| PREGABALIN | 347 | 0.3% | 12 | 190 | 34 |
| SERTRALINE | 319 | 0.5% | 9 | 168 | 10 |
| LAMOTRIGINE | 303 | 0.6% | 3 | 134 | 17 |
| BUPROPION | 290 | 0.8% | 34 | 240 | 60 |
| VENLAFAXINE | 290 | 0.6% | 5 | 144 | 25 |
| CLOZAPINE | 289 | 0.3% | 1 | 179 | 17 |
| MORPHINE | 256 | 0.2% | 20 | 125 | 30 |
| TRAMADOL | 244 | 0.3% | 10 | 154 | 25 |
| LEVOFLOXACIN | 213 | 0.5% | 0 | 148 | 8 |
| FENTANYL | 208 | 0.2% | 12 | 111 | 28 |
| BACLOFEN | 184 | 0.7% | 5 | 117 | 19 |
| LITHIUM | 177 | 1.2% | 4 | 125 | 23 |
| DULOXETINE | 174 | 0.3% | 2 | 102 | 18 |
| OLANZAPINE | 174 | 0.3% | 10 | 116 | 12 |
| FLUOXETINE | 171 | 0.6% | 2 | 135 | 40 |
| RISPERIDONE | 161 | 0.2% | 28 | 101 | 17 |
| CIPROFLOXACIN | 158 | 0.4% | 21 | 75 | 13 |