Negative pressure pulmonary oedema: Which Medications Cause It? (85 Reports Across 26 Drugs)
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Negative pressure pulmonary oedema has been reported as an adverse event with 26 different drugs in the FDA's FAERS database, with 85 total reports. 2 of these reports resulted in death.The drugs most commonly associated with Negative pressure pulmonary oedema are PROPOFOL, ROCURONIUM, and SUGAMMADEX.
85
Total Reports
26
Drugs Involved
2
Deaths
62
Hospitalizations
32.0 yrs
Average Patient Age
18.7% / 81.3%
Female / Male
Which Drugs Cause Negative pressure pulmonary oedema Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PROPOFOL | 54 | 0.3% | 1 | 42 | 25 |
| ROCURONIUM | 45 | 0.7% | 1 | 35 | 20 |
| SUGAMMADEX | 42 | 1.8% | 1 | 34 | 12 |
| SEVOFLURANE | 40 | 0.9% | 0 | 31 | 12 |
| FENTANYL | 36 | 0.0% | 0 | 32 | 13 |
| DEXAMETHASONE | 34 | 0.0% | 2 | 29 | 11 |
| ROPIVACAINE | 29 | 1.0% | 0 | 28 | 12 |
| ACETAMINOPHEN | 28 | 0.0% | 0 | 27 | 11 |
| ONDANSETRON | 28 | 0.1% | 1 | 26 | 11 |
| REMIFENTANIL | 24 | 0.9% | 0 | 21 | 17 |
| PARECOXIB | 17 | 10.8% | 1 | 16 | 1 |
| METAMIZOLE | 16 | 0.3% | 0 | 16 | 0 |
| KETAMINE | 15 | 0.2% | 0 | 14 | 14 |
| SUFENTANIL | 15 | 0.4% | 0 | 9 | 11 |
| TRAMADOL | 15 | 0.0% | 0 | 15 | 0 |
| MIDAZOLAM | 13 | 0.1% | 1 | 10 | 8 |
| LIDOCAINE | 12 | 0.1% | 0 | 11 | 11 |
| SUCCINYLCHOLINE | 9 | 0.4% | 0 | 8 | 6 |
| DEXMEDETOMIDINE | 7 | 0.2% | 0 | 7 | 6 |
| FENTANYL\FENTANYL | 7 | 0.2% | 1 | 5 | 6 |