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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Oesophageal rupture: Which Medications Cause It? (559 Reports Across 54 Drugs)

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Oesophageal rupture has been reported as an adverse event with 54 different drugs in the FDA's FAERS database, with 559 total reports. 53 of these reports resulted in death.The drugs most commonly associated with Oesophageal rupture are ADALIMUMAB, IBUPROFEN, and PREDNISOLONE.

559
Total Reports
54
Drugs Involved
53
Deaths
380
Hospitalizations
57.6 yrs
Average Patient Age
47.5% / 52.5%
Female / Male

Which Drugs Cause Oesophageal rupture Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ADALIMUMAB 33 0.0% 2 18 0
IBUPROFEN 23 0.0% 0 12 3
PREDNISOLONE 19 0.0% 2 18 13
TOCILIZUMAB 17 0.0% 0 13 13
RITUXIMAB 14 0.0% 1 9 0
BETHANECHOL 13 8.7% 0 13 13
CHOLECALCIFEROL 13 0.1% 0 13 13
METHYLPREDNISOLONE 13 0.0% 2 11 0
TAMSULOSIN 13 0.1% 0 13 13
OXYCODONE 12 0.0% 2 10 2
RIVAROXABAN 12 0.0% 2 9 3
RISEDRONATE 11 0.2% 0 11 11
TIRZEPATIDE 11 0.0% 0 9 3
LENALIDOMIDE 10 0.0% 2 8 1
NINTEDANIB 10 0.0% 0 8 2
APIXABAN 9 0.0% 2 9 0
ASPIRIN 9 0.0% 2 9 4
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM 9 0.0% 1 9 0
TREPROSTINIL 9 0.0% 0 8 1
BEVACIZUMAB 8 0.0% 2 3 1

View all 54 drugs →

Top 3 Drugs Associated With Oesophageal rupture

33 reports
23 reports
19 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)