Opisthotonus: Which Medications Cause It? (515 Reports Across 47 Drugs)
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Opisthotonus has been reported as an adverse event with 47 different drugs in the FDA's FAERS database, with 515 total reports. 22 of these reports resulted in death.The drugs most commonly associated with Opisthotonus are MORPHINE, OXYCODONE, and FENTANYL.
515
Total Reports
47
Drugs Involved
22
Deaths
341
Hospitalizations
32.0 yrs
Average Patient Age
37.4% / 62.6%
Female / Male
Which Drugs Cause Opisthotonus Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MORPHINE | 133 | 0.1% | 0 | 132 | 1 |
| OXYCODONE | 132 | 0.1% | 1 | 131 | 0 |
| FENTANYL | 130 | 0.1% | 0 | 127 | 0 |
| HYDROMORPHONE | 129 | 0.2% | 1 | 129 | 0 |
| ACETAMINOPHEN\HYDROCODONE | 126 | 0.1% | 1 | 126 | 0 |
| ACETAMINOPHEN\OXYCODONE | 126 | 0.1% | 0 | 126 | 0 |
| OXYMORPHONE | 126 | 0.3% | 0 | 126 | 0 |
| ASPIRIN\OXYCODONE\OXYCODONE TEREPHTHALATE | 120 | 37.0% | 0 | 120 | 0 |
| RISPERIDONE | 42 | 0.1% | 9 | 34 | 5 |
| VENLAFAXINE | 30 | 0.1% | 2 | 12 | 2 |
| GABAPENTIN | 27 | 0.0% | 0 | 21 | 0 |
| ONDANSETRON | 27 | 0.1% | 0 | 15 | 6 |
| QUETIAPINE | 25 | 0.0% | 0 | 14 | 0 |
| ACETAMINOPHEN | 22 | 0.0% | 0 | 8 | 0 |
| PROMETHAZINE | 20 | 0.3% | 0 | 20 | 0 |
| PROPOFOL | 20 | 0.1% | 0 | 12 | 5 |
| DIAZEPAM | 17 | 0.0% | 6 | 15 | 2 |
| MIRTAZAPINE | 16 | 0.1% | 7 | 15 | 1 |
| TRAMADOL | 13 | 0.0% | 0 | 13 | 0 |
| CITALOPRAM HYDROBROMIDE | 11 | 0.0% | 0 | 10 | 0 |