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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Oral discomfort: Which Medications Cause It? (9,852 Reports Across 453 Drugs)

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Oral discomfort has been reported as an adverse event with 453 different drugs in the FDA's FAERS database, with 9,852 total reports. 138 of these reports resulted in death.The drugs most commonly associated with Oral discomfort are NICOTINE, IBUPROFEN, and ADALIMUMAB.

9,852
Total Reports
453
Drugs Involved
138
Deaths
1,194
Hospitalizations
59.3 yrs
Average Patient Age
73.9% / 26.1%
Female / Male

Which Drugs Cause Oral discomfort Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
NICOTINE 445 1.4% 0 1 0
IBUPROFEN 360 0.4% 0 13 1
ADALIMUMAB 313 0.1% 0 31 10
CABOZANTINIB S-MALATE 282 0.7% 7 32 1
METHOTREXATE 278 0.1% 4 21 17
ETANERCEPT 259 0.1% 0 5 7
TOFACITINIB 235 0.2% 2 3 7
LEFLUNOMIDE 220 0.4% 0 4 7
RITUXIMAB 220 0.1% 0 6 8
TOCILIZUMAB 216 0.2% 0 4 7
SUNITINIB MALATE 210 1.0% 11 71 1
ABATACEPT 205 0.2% 0 2 7
HYDROXYCHLOROQUINE 199 0.3% 0 4 8
GOLIMUMAB 180 0.3% 0 2 7
SULFASALAZINE 165 0.4% 0 1 7
CERTOLIZUMAB PEGOL 154 0.2% 0 1 7
DOCOSANOL 142 1.8% 0 1 0
ALBUTEROL 132 0.1% 0 9 0
DUPILUMAB 132 0.0% 0 6 1
FLUTICASONE\SALMETEROL 126 0.3% 0 12 0

View all 453 drugs →

Top 3 Drugs Associated With Oral discomfort

445 reports
360 reports
313 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)