Ovarian failure: Which Medications Cause It? (379 Reports Across 67 Drugs)
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Ovarian failure has been reported as an adverse event with 67 different drugs in the FDA's FAERS database, with 379 total reports. 3 of these reports resulted in death.The drugs most commonly associated with Ovarian failure are ETOPOSIDE, DOXORUBICIN, and CYCLOPHOSPHAMIDE.
379
Total Reports
67
Drugs Involved
3
Deaths
34
Hospitalizations
27.1 yrs
Average Patient Age
100.0% / 0.0%
Female / Male
Which Drugs Cause Ovarian failure Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ETOPOSIDE | 114 | 0.2% | 0 | 3 | 0 |
| DOXORUBICIN | 113 | 0.1% | 0 | 3 | 0 |
| CYCLOPHOSPHAMIDE | 108 | 0.1% | 1 | 14 | 0 |
| VINCRISTINE | 101 | 0.1% | 0 | 4 | 0 |
| DACTINOMYCIN | 92 | 3.2% | 0 | 1 | 0 |
| IFOSFAMIDE | 91 | 0.5% | 0 | 3 | 0 |
| BUSULFAN | 51 | 0.5% | 0 | 3 | 0 |
| METHOTREXATE | 26 | 0.0% | 0 | 2 | 0 |
| PACLITAXEL | 25 | 0.0% | 0 | 6 | 0 |
| ADALIMUMAB | 22 | 0.0% | 0 | 1 | 0 |
| EPIRUBICIN | 22 | 0.1% | 0 | 6 | 0 |
| FLUOROURACIL | 22 | 0.0% | 0 | 0 | 0 |
| CARBOPLATIN | 20 | 0.0% | 0 | 6 | 0 |
| CHLORPROMAZINE | 17 | 0.4% | 0 | 0 | 0 |
| HYDRALAZINE | 17 | 0.3% | 0 | 0 | 0 |
| METHYLDOPA | 17 | 0.7% | 0 | 0 | 0 |
| MINOCYCLINE | 17 | 0.3% | 0 | 0 | 0 |
| PROCAINAMIDE | 17 | 7.5% | 0 | 0 | 0 |
| VORICONAZOLE | 17 | 0.1% | 0 | 0 | 0 |
| TERBINAFINE | 16 | 0.2% | 0 | 0 | 0 |