Paradoxical drug reaction: Which Medications Cause It? (2,817 Reports Across 233 Drugs)
Boost Your Natural Energy & Metabolism
Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.
Paradoxical drug reaction has been reported as an adverse event with 233 different drugs in the FDA's FAERS database, with 2,817 total reports. 112 of these reports resulted in death.The drugs most commonly associated with Paradoxical drug reaction are RIFAMPIN, ISONIAZID, and ETHAMBUTOL.
2,817
Total Reports
233
Drugs Involved
112
Deaths
886
Hospitalizations
41.9 yrs
Average Patient Age
52.8% / 47.2%
Female / Male
Which Drugs Cause Paradoxical drug reaction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| RIFAMPIN | 570 | 4.3% | 23 | 226 | 6 |
| ISONIAZID | 433 | 5.7% | 23 | 212 | 7 |
| ETHAMBUTOL | 407 | 5.4% | 24 | 201 | 6 |
| PYRAZINAMIDE | 407 | 7.4% | 23 | 196 | 5 |
| LEVETIRACETAM | 245 | 0.4% | 0 | 20 | 8 |
| PREDNISONE | 188 | 0.1% | 11 | 65 | 4 |
| ADALIMUMAB | 177 | 0.0% | 5 | 74 | 0 |
| DEXAMETHASONE | 110 | 0.1% | 5 | 61 | 4 |
| GABAPENTIN | 110 | 0.2% | 0 | 9 | 0 |
| INFLIXIMAB | 108 | 0.1% | 2 | 34 | 0 |
| QUETIAPINE | 107 | 0.2% | 35 | 56 | 3 |
| OLANZAPINE | 103 | 0.2% | 20 | 56 | 1 |
| ARIPIPRAZOLE | 102 | 0.2% | 28 | 18 | 0 |
| CLARITHROMYCIN | 98 | 0.5% | 1 | 20 | 1 |
| MOXIFLOXACIN | 89 | 0.6% | 1 | 44 | 1 |
| LORAZEPAM | 88 | 0.3% | 15 | 48 | 2 |
| VENLAFAXINE | 83 | 0.2% | 0 | 13 | 2 |
| CLONIDINE | 82 | 0.7% | 0 | 20 | 1 |
| LAMOTRIGINE | 79 | 0.2% | 0 | 11 | 1 |
| TRAZODONE | 79 | 0.4% | 0 | 8 | 0 |