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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Peptic ulcer: Which Medications Cause It? (2,049 Reports Across 207 Drugs)

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Peptic ulcer has been reported as an adverse event with 207 different drugs in the FDA's FAERS database, with 2,049 total reports. 163 of these reports resulted in death.The drugs most commonly associated with Peptic ulcer are IBUPROFEN, OLMESARTAN MEDOXOMIL, and ASPIRIN.

2,049
Total Reports
207
Drugs Involved
163
Deaths
1,062
Hospitalizations
60.0 yrs
Average Patient Age
58.1% / 41.9%
Female / Male

Which Drugs Cause Peptic ulcer Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
IBUPROFEN 175 0.2% 16 92 25
OLMESARTAN MEDOXOMIL 173 1.5% 5 120 2
ASPIRIN 146 0.2% 10 81 13
HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL 116 2.0% 2 84 2
METHOTREXATE 92 0.0% 2 22 4
DICLOFENAC 89 0.1% 6 30 3
PREDNISONE 75 0.1% 5 30 1
ADALIMUMAB 71 0.0% 2 25 0
ALENDRONATE 70 0.3% 6 67 3
NAPROXEN 68 0.1% 1 25 3
ACETAMINOPHEN 62 0.1% 16 23 21
APIXABAN 59 0.0% 5 42 8
DENOSUMAB 57 0.0% 1 13 0
LEFLUNOMIDE 55 0.1% 0 3 4
PANTOPRAZOLE 51 0.1% 2 13 0
CLOPIDOGREL BISULFATE 49 0.1% 2 39 3
SECUKINUMAB 48 0.0% 0 4 0
FLUTICASONE\SALMETEROL 46 0.1% 15 5 16
PREDNISOLONE 46 0.1% 5 19 6
ESOMEPRAZOLE 41 0.1% 18 6 16

View all 207 drugs →

Top 3 Drugs Associated With Peptic ulcer

175 reports
173 reports
146 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)