Peritoneal perforation: Which Medications Cause It? (113 Reports Across 19 Drugs)
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Peritoneal perforation has been reported as an adverse event with 19 different drugs in the FDA's FAERS database, with 113 total reports. 25 of these reports resulted in death.The drugs most commonly associated with Peritoneal perforation are CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM, CALCIUM\ICODEXTRIN\MAGNESIUM\SODIUM\SODIUM, and METHOTREXATE.
113
Total Reports
19
Drugs Involved
25
Deaths
61
Hospitalizations
59.5 yrs
Average Patient Age
52.7% / 47.3%
Female / Male
Which Drugs Cause Peritoneal perforation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM | 36 | 0.0% | 0 | 25 | 0 |
| CALCIUM\ICODEXTRIN\MAGNESIUM\SODIUM\SODIUM | 12 | 0.1% | 0 | 8 | 0 |
| METHOTREXATE | 9 | 0.0% | 0 | 8 | 0 |
| BUTALBITAL | 7 | 1.6% | 7 | 0 | 1 |
| CITALOPRAM HYDROBROMIDE | 7 | 0.0% | 7 | 0 | 1 |
| DIAZEPAM | 7 | 0.0% | 7 | 0 | 1 |
| FLUNITRAZEPAM | 7 | 0.7% | 7 | 0 | 1 |
| OMALIZUMAB | 7 | 0.0% | 0 | 7 | 0 |
| TRAZODONE | 7 | 0.0% | 7 | 0 | 1 |
| ZOLPIDEM\ZOLPIDEM | 7 | 0.1% | 7 | 0 | 1 |
| BISOPROLOL | 6 | 0.0% | 6 | 0 | 1 |
| LOPERAMIDE | 6 | 0.0% | 6 | 0 | 1 |
| METOCLOPRAMIDE | 6 | 0.1% | 6 | 0 | 1 |
| PROPYPHENAZONE | 6 | 13.3% | 6 | 0 | 1 |
| TRAMADOL | 6 | 0.0% | 6 | 0 | 1 |
| ADALIMUMAB | 5 | 0.0% | 1 | 3 | 0 |
| BEVACIZUMAB | 5 | 0.0% | 2 | 2 | 0 |
| DIPYRONE | 5 | 0.6% | 5 | 0 | 1 |
| PHENOBARBITAL | 5 | 0.1% | 5 | 0 | 1 |
Top 3 Drugs Associated With Peritoneal perforation
36 reports
12 reports
9 reports