Potentiating drug interaction: Which Medications Cause It? (2,384 Reports Across 222 Drugs)
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Potentiating drug interaction has been reported as an adverse event with 222 different drugs in the FDA's FAERS database, with 2,384 total reports. 227 of these reports resulted in death.The drugs most commonly associated with Potentiating drug interaction are METFORMIN, METHOTREXATE, and QUETIAPINE.
2,384
Total Reports
222
Drugs Involved
227
Deaths
1,177
Hospitalizations
56.8 yrs
Average Patient Age
49.9% / 50.1%
Female / Male
Which Drugs Cause Potentiating drug interaction Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METFORMIN | 150 | 0.2% | 21 | 135 | 18 |
| METHOTREXATE | 119 | 0.1% | 0 | 95 | 24 |
| QUETIAPINE | 98 | 0.1% | 20 | 39 | 14 |
| ASPIRIN | 87 | 0.1% | 5 | 61 | 6 |
| RIVAROXABAN | 71 | 0.1% | 5 | 44 | 14 |
| PREGABALIN | 67 | 0.1% | 17 | 25 | 20 |
| TACROLIMUS | 56 | 0.1% | 0 | 44 | 17 |
| AMIODARONE | 53 | 0.2% | 4 | 25 | 9 |
| CLARITHROMYCIN | 52 | 0.3% | 4 | 32 | 3 |
| GABAPENTIN | 52 | 0.1% | 5 | 26 | 7 |
| VINCRISTINE | 52 | 0.1% | 1 | 36 | 3 |
| WARFARIN | 51 | 0.1% | 1 | 19 | 0 |
| DEXAMETHASONE | 48 | 0.0% | 0 | 42 | 4 |
| PEGASPARGASE | 47 | 0.4% | 1 | 32 | 3 |
| AMLODIPINE | 46 | 0.1% | 1 | 27 | 9 |
| ATORVASTATIN | 46 | 0.1% | 1 | 33 | 10 |
| TRAMADOL | 44 | 0.1% | 16 | 23 | 1 |
| SERTRALINE | 43 | 0.1% | 19 | 6 | 3 |
| DIAZEPAM | 42 | 0.1% | 28 | 3 | 13 |
| RISPERIDONE | 42 | 0.1% | 14 | 17 | 12 |