Pre-existing disease: Which Medications Cause It? (251 Reports Across 19 Drugs)
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Pre-existing disease has been reported as an adverse event with 19 different drugs in the FDA's FAERS database, with 251 total reports. 140 of these reports resulted in death.The drugs most commonly associated with Pre-existing disease are PREDNISONE, COAGULATION FACTOR VIIA RECOMBINANT HUMAN, and CYCLOPHOSPHAMIDE.
251
Total Reports
19
Drugs Involved
140
Deaths
67
Hospitalizations
61.0 yrs
Average Patient Age
63.5% / 36.5%
Female / Male
Which Drugs Cause Pre-existing disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PREDNISONE | 79 | 0.1% | 78 | 23 | 0 |
| COAGULATION FACTOR VIIA RECOMBINANT HUMAN | 78 | 8.2% | 78 | 22 | 0 |
| CYCLOPHOSPHAMIDE | 78 | 0.1% | 78 | 22 | 0 |
| RITUXIMAB | 77 | 0.0% | 77 | 21 | 0 |
| ANTI-INHIBITOR COAGULANT COMPLEX | 74 | 5.2% | 74 | 22 | 0 |
| ANTIHEMOPHILIC FACTOR HUMAN | 36 | 4.5% | 36 | 13 | 0 |
| COAGULATION FACTOR VII HUMAN | 25 | 43.9% | 25 | 18 | 0 |
| ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT | 18 | 0.2% | 18 | 7 | 0 |
| THROMBOPLASTIN | 14 | 93.3% | 14 | 6 | 0 |
| RISPERIDONE | 13 | 0.0% | 0 | 2 | 0 |
| OMEPRAZOLE | 8 | 0.0% | 0 | 0 | 0 |
| BACLOFEN | 7 | 0.0% | 5 | 3 | 1 |
| RIVAROXABAN | 7 | 0.0% | 2 | 4 | 0 |
| MICONAZOLE | 6 | 0.1% | 0 | 0 | 0 |
| NICOTINE | 6 | 0.0% | 0 | 0 | 0 |
| ACETAMINOPHEN | 5 | 0.0% | 1 | 2 | 0 |
| AZTREONAM | 5 | 0.3% | 5 | 0 | 5 |
| LINEZOLID | 5 | 0.0% | 5 | 0 | 5 |
| METRONIDAZOLE | 5 | 0.0% | 5 | 0 | 5 |
Top 3 Drugs Associated With Pre-existing disease
79 reports
78 reports
78 reports