Premature separation of placenta: Which Medications Cause It? (977 Reports Across 96 Drugs)
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Premature separation of placenta has been reported as an adverse event with 96 different drugs in the FDA's FAERS database, with 977 total reports. 37 of these reports resulted in death.The drugs most commonly associated with Premature separation of placenta are HYDROXYPROGESTERONE CAPROATE, ADALIMUMAB, and DINOPROSTONE.
977
Total Reports
96
Drugs Involved
37
Deaths
349
Hospitalizations
31.0 yrs
Average Patient Age
99.1% / 0.9%
Female / Male
Which Drugs Cause Premature separation of placenta Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| HYDROXYPROGESTERONE CAPROATE | 114 | 0.5% | 0 | 97 | 1 |
| ADALIMUMAB | 62 | 0.0% | 0 | 26 | 0 |
| DINOPROSTONE | 48 | 6.6% | 0 | 7 | 10 |
| ASPIRIN | 38 | 0.0% | 11 | 9 | 1 |
| HYDROXYCHLOROQUINE | 36 | 0.1% | 19 | 8 | 0 |
| AZATHIOPRINE | 34 | 0.1% | 16 | 7 | 1 |
| MISOPROSTOL | 33 | 0.9% | 0 | 9 | 3 |
| PREDNISONE | 30 | 0.0% | 17 | 6 | 1 |
| INTERFERON BETA-1A | 28 | 0.0% | 0 | 5 | 0 |
| BUPRENORPHINE | 26 | 0.0% | 0 | 11 | 0 |
| ESOMEPRAZOLE | 26 | 0.0% | 8 | 12 | 0 |
| ENOXAPARIN | 24 | 0.1% | 1 | 7 | 1 |
| FLUOXETINE | 20 | 0.1% | 0 | 8 | 1 |
| DOLUTEGRAVIR | 19 | 0.2% | 0 | 0 | 0 |
| EMTRICITABINE\TENOFOVIR DISOPROXIL | 19 | 0.1% | 0 | 2 | 0 |
| NATALIZUMAB | 19 | 0.0% | 0 | 2 | 0 |
| VENLAFAXINE | 18 | 0.0% | 1 | 4 | 7 |
| BUPRENORPHINE\NALOXONE | 17 | 0.1% | 0 | 1 | 0 |
| LEVETIRACETAM | 17 | 0.0% | 0 | 2 | 1 |
| LEVONORGESTREL | 17 | 0.0% | 0 | 6 | 4 |