Product size issue: Which Medications Cause It? (4,631 Reports Across 160 Drugs)
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Product size issue has been reported as an adverse event with 160 different drugs in the FDA's FAERS database, with 4,631 total reports. 103 of these reports resulted in death.The drugs most commonly associated with Product size issue are ENZALUTAMIDE, DIMETHICONE\LOPERAMIDE, and ACETAMINOPHEN.
4,631
Total Reports
160
Drugs Involved
103
Deaths
249
Hospitalizations
67.9 yrs
Average Patient Age
58.1% / 41.9%
Female / Male
Which Drugs Cause Product size issue Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ENZALUTAMIDE | 539 | 1.1% | 65 | 68 | 6 |
| DIMETHICONE\LOPERAMIDE | 416 | 7.4% | 0 | 1 | 0 |
| ACETAMINOPHEN | 150 | 0.1% | 0 | 1 | 0 |
| NIRMATRELVIR\RITONAVIR | 140 | 0.3% | 0 | 1 | 2 |
| ESTRADIOL | 120 | 0.4% | 0 | 3 | 0 |
| ABIRATERONE | 115 | 0.3% | 8 | 8 | 0 |
| GUAIFENESIN | 111 | 1.4% | 0 | 1 | 0 |
| IBUPROFEN | 102 | 0.1% | 0 | 4 | 2 |
| DEXTROMETHORPHAN HYDROBROMIDE\GUAIFENESIN | 101 | 1.5% | 0 | 1 | 1 |
| RIVAROXABAN | 92 | 0.1% | 0 | 8 | 0 |
| LOPERAMIDE | 88 | 0.5% | 0 | 0 | 0 |
| ICOSAPENT ETHYL | 84 | 2.2% | 0 | 3 | 0 |
| MINERALS\VITAMINS | 65 | 4.1% | 0 | 0 | 0 |
| OXYCODONE | 65 | 0.0% | 0 | 3 | 0 |
| ELACESTRANT | 58 | 0.8% | 3 | 11 | 0 |
| BUPRENORPHINE | 55 | 0.1% | 0 | 0 | 0 |
| NAPROXEN | 52 | 0.1% | 0 | 1 | 3 |
| AMLODIPINE | 49 | 0.1% | 1 | 0 | 0 |
| OMEPRAZOLE | 47 | 0.1% | 0 | 0 | 0 |
| VOXELOTOR | 47 | 0.2% | 0 | 12 | 0 |