Psychiatric decompensation: Which Medications Cause It? (1,541 Reports Across 126 Drugs)
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Psychiatric decompensation has been reported as an adverse event with 126 different drugs in the FDA's FAERS database, with 1,541 total reports. 61 of these reports resulted in death.The drugs most commonly associated with Psychiatric decompensation are CLOZAPINE, ARIPIPRAZOLE, and QUETIAPINE.
1,541
Total Reports
126
Drugs Involved
61
Deaths
1,163
Hospitalizations
46.9 yrs
Average Patient Age
41.9% / 58.1%
Female / Male
Which Drugs Cause Psychiatric decompensation Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CLOZAPINE | 368 | 0.4% | 17 | 299 | 8 |
| ARIPIPRAZOLE | 291 | 0.4% | 9 | 229 | 5 |
| QUETIAPINE | 212 | 0.3% | 12 | 197 | 24 |
| RISPERIDONE | 176 | 0.2% | 13 | 149 | 0 |
| BUPROPION | 152 | 0.4% | 11 | 132 | 0 |
| OLANZAPINE | 135 | 0.3% | 4 | 80 | 2 |
| RALTEGRAVIR | 132 | 1.5% | 9 | 114 | 0 |
| EFAVIRENZ | 131 | 1.7% | 10 | 129 | 0 |
| CLONAZEPAM | 128 | 0.3% | 11 | 119 | 0 |
| ATAZANAVIR | 123 | 2.3% | 13 | 122 | 0 |
| RITONAVIR | 115 | 1.0% | 7 | 106 | 0 |
| SERTRALINE | 107 | 0.2% | 10 | 98 | 0 |
| CITALOPRAM HYDROBROMIDE | 104 | 0.4% | 3 | 104 | 0 |
| ZOPICLONE | 99 | 0.7% | 10 | 90 | 0 |
| LOPINAVIR\RITONAVIR | 95 | 1.2% | 11 | 95 | 0 |
| VALPROIC ACID | 93 | 0.5% | 14 | 87 | 0 |
| LAMIVUDINE | 88 | 0.5% | 8 | 88 | 0 |
| ENFUVIRTIDE | 82 | 10.8% | 8 | 82 | 0 |
| TENOFOVIR DISOPROXIL | 64 | 0.2% | 9 | 63 | 0 |
| PALIPERIDONE | 57 | 0.1% | 1 | 46 | 3 |