Pulmonary arterial hypertension: Which Medications Cause It? (11,941 Reports Across 297 Drugs)
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Pulmonary arterial hypertension has been reported as an adverse event with 297 different drugs in the FDA's FAERS database, with 11,941 total reports. 4,263 of these reports resulted in death.The drugs most commonly associated with Pulmonary arterial hypertension are TREPROSTINIL, MACITENTAN, and AMBRISENTAN.
11,941
Total Reports
297
Drugs Involved
4,263
Deaths
7,773
Hospitalizations
56.6 yrs
Average Patient Age
70.5% / 29.5%
Female / Male
Which Drugs Cause Pulmonary arterial hypertension Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TREPROSTINIL | 3,240 | 3.5% | 978 | 2,289 | 135 |
| MACITENTAN | 2,390 | 5.3% | 1,204 | 1,695 | 111 |
| AMBRISENTAN | 1,965 | 2.3% | 432 | 1,266 | 41 |
| SELEXIPAG | 1,387 | 7.5% | 712 | 917 | 74 |
| EPOPROSTENOL | 1,055 | 7.9% | 475 | 864 | 58 |
| BOSENTAN | 778 | 4.0% | 358 | 506 | 36 |
| TADALAFIL | 680 | 2.2% | 267 | 396 | 33 |
| SILDENAFIL | 487 | 1.4% | 158 | 279 | 31 |
| RIOCIGUAT | 436 | 2.4% | 175 | 319 | 17 |
| ILOPROST | 284 | 5.7% | 169 | 177 | 13 |
| BOSENTAN\BOSENTAN | 245 | 7.0% | 149 | 143 | 13 |
| CYCLOPHOSPHAMIDE | 156 | 0.1% | 58 | 112 | 35 |
| DASATINIB | 137 | 0.5% | 6 | 66 | 22 |
| TRACLEER | 127 | 6.8% | 85 | 70 | 9 |
| FUROSEMIDE | 111 | 0.2% | 31 | 85 | 15 |
| METHOTREXATE | 97 | 0.0% | 36 | 82 | 19 |
| CARBOPLATIN | 92 | 0.1% | 40 | 63 | 7 |
| RITUXIMAB | 92 | 0.1% | 41 | 59 | 21 |
| THIOTEPA | 82 | 1.2% | 41 | 55 | 13 |
| LETAIRIS | 60 | 1.4% | 15 | 40 | 0 |