Pulmonary valve incompetence: Which Medications Cause It? (803 Reports Across 74 Drugs)
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Pulmonary valve incompetence has been reported as an adverse event with 74 different drugs in the FDA's FAERS database, with 803 total reports. 53 of these reports resulted in death.The drugs most commonly associated with Pulmonary valve incompetence are FENFLURAMINE, ONDANSETRON, and CLOZAPINE.
803
Total Reports
74
Drugs Involved
53
Deaths
336
Hospitalizations
43.8 yrs
Average Patient Age
54.2% / 45.8%
Female / Male
Which Drugs Cause Pulmonary valve incompetence Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| FENFLURAMINE | 163 | 4.1% | 0 | 32 | 1 |
| ONDANSETRON | 97 | 0.4% | 3 | 18 | 5 |
| CLOZAPINE | 69 | 0.1% | 0 | 17 | 1 |
| ARIPIPRAZOLE | 30 | 0.1% | 0 | 3 | 0 |
| ZOMETA | 28 | 3.2% | 6 | 17 | 0 |
| AREDIA | 23 | 13.9% | 5 | 15 | 0 |
| VALSARTAN | 23 | 0.1% | 0 | 23 | 0 |
| HYDROCHLOROTHIAZIDE\VALSARTAN | 20 | 0.3% | 0 | 19 | 0 |
| DIAZEPAM | 19 | 0.1% | 0 | 5 | 3 |
| ATORVASTATIN | 18 | 0.0% | 0 | 1 | 1 |
| FLUOXETINE | 18 | 0.1% | 1 | 7 | 10 |
| METFORMIN | 18 | 0.0% | 1 | 2 | 0 |
| OLANZAPINE | 18 | 0.0% | 0 | 6 | 0 |
| METOPROLOL | 17 | 0.0% | 2 | 16 | 0 |
| AMLODIPINE | 16 | 0.0% | 0 | 13 | 0 |
| HYDROCHLOROTHIAZIDE | 15 | 0.1% | 0 | 11 | 0 |
| OCTREOTIDE | 15 | 0.1% | 1 | 13 | 0 |
| PROPRANOLOL | 15 | 0.1% | 0 | 15 | 0 |
| SACUBITRIL\VALSARTAN | 15 | 0.0% | 5 | 10 | 0 |
| SERTRALINE | 14 | 0.0% | 0 | 5 | 3 |