Pulmonary veno-occlusive disease: Which Medications Cause It? (550 Reports Across 52 Drugs)
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Pulmonary veno-occlusive disease has been reported as an adverse event with 52 different drugs in the FDA's FAERS database, with 550 total reports. 173 of these reports resulted in death.The drugs most commonly associated with Pulmonary veno-occlusive disease are TREPROSTINIL, MACITENTAN, and EPOPROSTENOL.
550
Total Reports
52
Drugs Involved
173
Deaths
311
Hospitalizations
50.7 yrs
Average Patient Age
64.0% / 36.0%
Female / Male
Which Drugs Cause Pulmonary veno-occlusive disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TREPROSTINIL | 98 | 0.1% | 29 | 66 | 17 |
| MACITENTAN | 90 | 0.2% | 26 | 58 | 7 |
| EPOPROSTENOL | 67 | 0.5% | 25 | 47 | 7 |
| SELEXIPAG | 66 | 0.4% | 19 | 42 | 4 |
| SILDENAFIL | 57 | 0.2% | 21 | 26 | 7 |
| AMBRISENTAN | 54 | 0.1% | 18 | 34 | 7 |
| CYCLOPHOSPHAMIDE | 45 | 0.0% | 13 | 21 | 8 |
| MITOMYCIN | 43 | 2.0% | 6 | 23 | 6 |
| TADALAFIL | 41 | 0.1% | 9 | 21 | 1 |
| BOSENTAN | 39 | 0.2% | 12 | 22 | 2 |
| BUSULFAN | 33 | 0.3% | 9 | 6 | 4 |
| FLUDARABINE | 22 | 0.1% | 6 | 3 | 0 |
| CARBOPLATIN | 21 | 0.0% | 4 | 13 | 4 |
| ETOPOSIDE | 21 | 0.0% | 4 | 9 | 1 |
| THIOTEPA | 21 | 0.3% | 6 | 7 | 4 |
| MELPHALAN | 20 | 0.1% | 7 | 5 | 3 |
| RIOCIGUAT | 18 | 0.1% | 2 | 13 | 2 |
| DOXORUBICIN | 17 | 0.0% | 6 | 5 | 0 |
| VINCRISTINE | 16 | 0.0% | 4 | 8 | 1 |
| FLUOROURACIL | 15 | 0.0% | 1 | 5 | 2 |