Rebound effect: Which Medications Cause It? (9,849 Reports Across 341 Drugs)
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Rebound effect has been reported as an adverse event with 341 different drugs in the FDA's FAERS database, with 9,849 total reports. 232 of these reports resulted in death.The drugs most commonly associated with Rebound effect are OMEPRAZOLE, DUPILUMAB, and LANSOPRAZOLE.
9,849
Total Reports
341
Drugs Involved
232
Deaths
1,464
Hospitalizations
47.0 yrs
Average Patient Age
59.7% / 40.3%
Female / Male
Which Drugs Cause Rebound effect Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OMEPRAZOLE | 2,335 | 2.7% | 51 | 14 | 1 |
| DUPILUMAB | 2,192 | 0.6% | 1 | 75 | 9 |
| LANSOPRAZOLE | 1,561 | 2.6% | 54 | 24 | 0 |
| ESOMEPRAZOLE | 1,493 | 2.0% | 47 | 12 | 0 |
| PANTOPRAZOLE | 956 | 1.2% | 43 | 17 | 0 |
| PREDNISONE | 806 | 0.5% | 30 | 252 | 39 |
| DEXLANSOPRAZOLE | 572 | 2.4% | 39 | 0 | 0 |
| DENOSUMAB | 478 | 0.3% | 1 | 88 | 2 |
| FINGOLIMOD | 379 | 0.5% | 11 | 114 | 12 |
| NIRMATRELVIR\RITONAVIR | 342 | 0.7% | 0 | 5 | 2 |
| PREDNISOLONE | 331 | 0.4% | 21 | 132 | 27 |
| METHOTREXATE | 245 | 0.1% | 13 | 65 | 14 |
| METHYLPREDNISOLONE | 227 | 0.4% | 40 | 118 | 25 |
| BRIMONIDINE | 206 | 1.7% | 0 | 0 | 0 |
| MYCOPHENOLATE MOFETIL | 188 | 0.3% | 15 | 44 | 3 |
| CYCLOSPORINE | 128 | 0.2% | 9 | 37 | 1 |
| AZATHIOPRINE | 116 | 0.4% | 8 | 28 | 6 |
| RITUXIMAB | 113 | 0.1% | 23 | 48 | 10 |
| DEXAMETHASONE | 104 | 0.1% | 19 | 49 | 7 |
| QUETIAPINE | 95 | 0.1% | 15 | 82 | 5 |