Renal tubular necrosis: Which Medications Cause It? (6,529 Reports Across 416 Drugs)
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Renal tubular necrosis has been reported as an adverse event with 416 different drugs in the FDA's FAERS database, with 6,529 total reports. 754 of these reports resulted in death.The drugs most commonly associated with Renal tubular necrosis are VANCOMYCIN, OMEPRAZOLE, and TACROLIMUS.
6,529
Total Reports
416
Drugs Involved
754
Deaths
4,545
Hospitalizations
56.3 yrs
Average Patient Age
45.1% / 54.9%
Female / Male
Which Drugs Cause Renal tubular necrosis Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| VANCOMYCIN | 681 | 2.0% | 29 | 509 | 36 |
| OMEPRAZOLE | 546 | 0.6% | 91 | 279 | 11 |
| TACROLIMUS | 536 | 0.6% | 72 | 332 | 77 |
| ESOMEPRAZOLE | 494 | 0.7% | 91 | 261 | 6 |
| PANTOPRAZOLE | 475 | 0.6% | 87 | 229 | 4 |
| LANSOPRAZOLE | 365 | 0.6% | 64 | 187 | 0 |
| IBUPROFEN | 324 | 0.4% | 11 | 246 | 46 |
| METFORMIN | 309 | 0.3% | 24 | 258 | 125 |
| MYCOPHENOLATE MOFETIL | 305 | 0.4% | 48 | 210 | 59 |
| PREDNISONE | 249 | 0.2% | 31 | 189 | 85 |
| PEMBROLIZUMAB | 246 | 0.3% | 8 | 125 | 13 |
| PIPERACILLIN\TAZOBACTAM | 239 | 1.3% | 11 | 173 | 14 |
| ACETAMINOPHEN | 234 | 0.2% | 52 | 193 | 47 |
| PEMETREXED | 220 | 0.9% | 4 | 120 | 3 |
| CARBOPLATIN | 218 | 0.3% | 7 | 133 | 2 |
| GENTAMICIN | 170 | 2.6% | 13 | 128 | 8 |
| ZOLEDRONIC ACID | 169 | 0.5% | 9 | 134 | 23 |
| CIPROFLOXACIN | 165 | 0.4% | 11 | 139 | 23 |
| FUROSEMIDE | 160 | 0.3% | 13 | 135 | 11 |
| CISPLATIN | 157 | 0.3% | 14 | 120 | 25 |