Respiratory depression: Which Medications Cause It? (8,084 Reports Across 425 Drugs)
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Respiratory depression has been reported as an adverse event with 425 different drugs in the FDA's FAERS database, with 8,084 total reports. 2,949 of these reports resulted in death.The drugs most commonly associated with Respiratory depression are MORPHINE, FENTANYL, and METHADONE.
8,084
Total Reports
425
Drugs Involved
2,949
Deaths
3,506
Hospitalizations
45.6 yrs
Average Patient Age
45.8% / 54.2%
Female / Male
Which Drugs Cause Respiratory depression Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| MORPHINE | 890 | 0.7% | 288 | 341 | 237 |
| FENTANYL | 811 | 0.9% | 295 | 342 | 166 |
| METHADONE | 759 | 2.9% | 345 | 358 | 111 |
| OXYCODONE | 662 | 0.4% | 284 | 273 | 131 |
| DIAZEPAM | 660 | 1.7% | 359 | 211 | 151 |
| ACETAMINOPHEN | 582 | 0.4% | 386 | 225 | 97 |
| TRAMADOL | 544 | 0.7% | 268 | 189 | 105 |
| GABAPENTIN | 458 | 0.6% | 135 | 232 | 73 |
| LORAZEPAM | 425 | 1.3% | 87 | 279 | 81 |
| PREGABALIN | 425 | 0.4% | 227 | 155 | 107 |
| QUETIAPINE | 403 | 0.6% | 222 | 181 | 111 |
| BACLOFEN | 364 | 1.4% | 21 | 259 | 67 |
| ALPRAZOLAM | 360 | 0.7% | 214 | 129 | 82 |
| BUPRENORPHINE | 334 | 0.4% | 131 | 133 | 49 |
| HYDROMORPHONE | 333 | 0.4% | 60 | 186 | 44 |
| OLANZAPINE | 311 | 0.6% | 160 | 122 | 61 |
| FLUOXETINE | 306 | 1.0% | 77 | 217 | 34 |
| CLONAZEPAM | 258 | 0.7% | 144 | 103 | 60 |
| ALCOHOL | 220 | 1.0% | 167 | 54 | 27 |
| DIPHENHYDRAMINE | 220 | 0.9% | 67 | 150 | 23 |