Retinal degeneration: Which Medications Cause It? (878 Reports Across 64 Drugs)
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Retinal degeneration has been reported as an adverse event with 64 different drugs in the FDA's FAERS database, with 878 total reports. 9 of these reports resulted in death.The drugs most commonly associated with Retinal degeneration are PENTOSAN POLYSULFATE, HYDROXYCHLOROQUINE, and RANIBIZUMAB.
878
Total Reports
64
Drugs Involved
9
Deaths
107
Hospitalizations
51.2 yrs
Average Patient Age
61.1% / 38.9%
Female / Male
Which Drugs Cause Retinal degeneration Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PENTOSAN POLYSULFATE | 92 | 2.1% | 0 | 0 | 0 |
| HYDROXYCHLOROQUINE | 63 | 0.1% | 0 | 4 | 0 |
| RANIBIZUMAB | 56 | 0.4% | 1 | 8 | 1 |
| AFLIBERCEPT | 54 | 0.2% | 1 | 2 | 0 |
| ADALIMUMAB | 49 | 0.0% | 0 | 7 | 1 |
| BEVACIZUMAB | 39 | 0.1% | 0 | 3 | 0 |
| BROLUCIZUMAB-DBLL | 30 | 1.1% | 0 | 0 | 0 |
| DEXAMETHASONE | 27 | 0.0% | 3 | 5 | 0 |
| VORETIGENE NEPARVOVEC | 25 | 65.8% | 0 | 0 | 0 |
| PREDNISONE | 24 | 0.0% | 0 | 9 | 0 |
| MELPHALAN | 21 | 0.1% | 0 | 1 | 3 |
| PREDNISOLONE | 21 | 0.0% | 0 | 12 | 0 |
| MYCOPHENOLATE MOFETIL | 19 | 0.0% | 0 | 6 | 0 |
| RITUXIMAB | 19 | 0.0% | 0 | 0 | 0 |
| TACROLIMUS | 19 | 0.0% | 0 | 9 | 1 |
| METHOTREXATE | 15 | 0.0% | 0 | 1 | 0 |
| VORETIGENE NEPARVOVEC-RZYL | 15 | 10.0% | 0 | 1 | 0 |
| TRIAMCINOLONE ACETONIDE | 12 | 0.1% | 0 | 2 | 0 |
| VIGABATRIN | 12 | 0.1% | 0 | 2 | 0 |
| FLUOCINOLONE ACETONIDE | 11 | 0.6% | 0 | 0 | 0 |