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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Retinal depigmentation: Which Medications Cause It? (237 Reports Across 22 Drugs)

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Retinal depigmentation has been reported as an adverse event with 22 different drugs in the FDA's FAERS database, with 237 total reports. 3 of these reports resulted in death.The drugs most commonly associated with Retinal depigmentation are RANIBIZUMAB, MELPHALAN, and PENTOSAN POLYSULFATE.

237
Total Reports
22
Drugs Involved
3
Deaths
10
Hospitalizations
55.8 yrs
Average Patient Age
68.4% / 31.6%
Female / Male

Which Drugs Cause Retinal depigmentation Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
RANIBIZUMAB 50 0.3% 1 1 0
MELPHALAN 31 0.2% 0 0 0
PENTOSAN POLYSULFATE 21 0.5% 0 0 0
CARBOPLATIN 20 0.0% 0 0 0
VERTEPORFIN 17 2.3% 0 0 0
HYDROXYCHLOROQUINE 16 0.0% 0 1 0
BEVACIZUMAB 14 0.0% 2 1 0
AFLIBERCEPT 13 0.1% 1 0 0
TOPOTECAN 13 0.4% 0 0 0
ACYCLOVIR 10 0.1% 0 1 0
ALEMTUZUMAB 10 0.1% 0 1 0
HYDROCHLOROTHIAZIDE 9 0.0% 0 4 4
METHYLPREDNISOLONE 9 0.0% 0 1 0
BROLUCIZUMAB-DBLL 8 0.3% 0 0 0
VINCRISTINE 8 0.0% 0 0 0
VORETIGENE NEPARVOVEC-RZYL 8 5.3% 0 0 0
ETOPOSIDE 7 0.0% 0 0 0
GABAPENTIN 7 0.0% 0 0 0
AMITRIPTYLINE 6 0.0% 0 0 0
ENTECAVIR 5 0.1% 0 0 0

View all 22 drugs →

Top 3 Drugs Associated With Retinal depigmentation

50 reports
31 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)