Retinal toxicity: Which Medications Cause It? (902 Reports Across 53 Drugs)
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Retinal toxicity has been reported as an adverse event with 53 different drugs in the FDA's FAERS database, with 902 total reports. 4 of these reports resulted in death.The drugs most commonly associated with Retinal toxicity are HYDROXYCHLOROQUINE, METHOTREXATE, and LEFLUNOMIDE.
902
Total Reports
53
Drugs Involved
4
Deaths
36
Hospitalizations
52.6 yrs
Average Patient Age
65.1% / 34.9%
Female / Male
Which Drugs Cause Retinal toxicity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| HYDROXYCHLOROQUINE | 320 | 0.5% | 0 | 8 | 0 |
| METHOTREXATE | 109 | 0.0% | 0 | 0 | 0 |
| LEFLUNOMIDE | 94 | 0.2% | 0 | 0 | 0 |
| ADALIMUMAB | 78 | 0.0% | 0 | 2 | 0 |
| TOCILIZUMAB | 72 | 0.1% | 0 | 0 | 0 |
| ETANERCEPT | 61 | 0.0% | 0 | 0 | 0 |
| DIDANOSINE | 55 | 2.7% | 0 | 0 | 0 |
| PENTOSAN POLYSULFATE | 55 | 1.2% | 0 | 0 | 0 |
| CEFUROXIME | 47 | 0.9% | 0 | 4 | 0 |
| MELPHALAN | 37 | 0.2% | 0 | 0 | 3 |
| EFAVIRENZ | 33 | 0.4% | 0 | 0 | 0 |
| CISPLATIN | 31 | 0.1% | 0 | 1 | 0 |
| PACLITAXEL | 26 | 0.0% | 1 | 0 | 0 |
| SILDENAFIL | 26 | 0.1% | 0 | 1 | 0 |
| TOFACITINIB | 26 | 0.0% | 0 | 0 | 0 |
| CARBOPLATIN | 23 | 0.0% | 0 | 0 | 0 |
| RITONAVIR | 23 | 0.2% | 0 | 0 | 0 |
| GEMCITABINE | 22 | 0.1% | 1 | 0 | 0 |
| AZATHIOPRINE | 20 | 0.1% | 0 | 0 | 0 |
| IVOSPEMIN | 19 | 79.2% | 1 | 0 | 0 |