Reversible cerebral vasoconstriction syndrome: Which Medications Cause It? (1,809 Reports Across 167 Drugs)
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Reversible cerebral vasoconstriction syndrome has been reported as an adverse event with 167 different drugs in the FDA's FAERS database, with 1,809 total reports. 74 of these reports resulted in death.The drugs most commonly associated with Reversible cerebral vasoconstriction syndrome are ESCITALOPRAM OXALATE, FLUOXETINE, and TACROLIMUS.
1,809
Total Reports
167
Drugs Involved
74
Deaths
1,209
Hospitalizations
44.0 yrs
Average Patient Age
84.1% / 15.9%
Female / Male
Which Drugs Cause Reversible cerebral vasoconstriction syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| ESCITALOPRAM OXALATE | 165 | 0.5% | 20 | 109 | 21 |
| FLUOXETINE | 154 | 0.5% | 0 | 123 | 0 |
| TACROLIMUS | 127 | 0.1% | 3 | 64 | 19 |
| METHYLPREDNISOLONE | 119 | 0.2% | 16 | 60 | 16 |
| SUMATRIPTAN | 105 | 0.6% | 7 | 49 | 7 |
| VENLAFAXINE | 105 | 0.2% | 10 | 75 | 15 |
| DULOXETINE | 102 | 0.2% | 0 | 68 | 7 |
| SERTRALINE | 102 | 0.2% | 5 | 77 | 7 |
| MYCOPHENOLATE MOFETIL | 68 | 0.1% | 0 | 27 | 2 |
| CITALOPRAM HYDROBROMIDE | 64 | 0.2% | 7 | 41 | 1 |
| PAROXETINE | 60 | 0.3% | 0 | 49 | 5 |
| BUPROPION | 53 | 0.2% | 0 | 22 | 5 |
| METHYLPHENIDATE | 50 | 0.2% | 0 | 39 | 0 |
| ARIPIPRAZOLE | 49 | 0.1% | 7 | 42 | 6 |
| PREDNISOLONE | 45 | 0.1% | 0 | 32 | 2 |
| IBUPROFEN | 43 | 0.1% | 0 | 21 | 1 |
| PREDNISONE | 43 | 0.0% | 1 | 30 | 0 |
| CETIRIZINE | 42 | 0.1% | 4 | 34 | 4 |
| CYCLOPHOSPHAMIDE | 42 | 0.0% | 3 | 20 | 0 |
| NICOTINE | 37 | 0.1% | 0 | 28 | 0 |