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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sedation: Which Medications Cause It? (18,005 Reports Across 617 Drugs)

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Sedation has been reported as an adverse event with 617 different drugs in the FDA's FAERS database, with 18,005 total reports. 598 of these reports resulted in death.The drugs most commonly associated with Sedation are ESKETAMINE, OLANZAPINE, and QUETIAPINE.

18,005
Total Reports
617
Drugs Involved
598
Deaths
5,532
Hospitalizations
48.6 yrs
Average Patient Age
56.1% / 43.9%
Female / Male

Which Drugs Cause Sedation Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
ESKETAMINE 2,244 14.8% 11 201 18
OLANZAPINE 2,130 4.1% 71 817 78
QUETIAPINE 2,051 2.8% 90 764 55
RISPERIDONE 1,863 2.4% 71 535 27
CLOZAPINE 1,748 1.8% 98 786 45
ARIPIPRAZOLE 1,603 2.4% 50 467 26
MORPHINE 1,265 1.1% 39 706 104
GABAPENTIN 980 1.3% 14 207 9
AMITRIPTYLINE 975 4.8% 37 567 94
PALIPERIDONE 873 2.1% 46 148 6
ACETAMINOPHEN 808 0.6% 9 397 71
CARBAMAZEPINE 779 3.2% 2 628 80
OXAZEPAM 709 5.7% 13 628 84
LEVOTHYROXINE 642 1.0% 3 592 70
OMEPRAZOLE 641 0.7% 4 615 79
CYCLOBENZAPRINE 636 7.0% 8 594 68
HYDROMORPHONE 632 0.8% 31 139 21
VENLAFAXINE 626 1.3% 4 137 16
AMLODIPINE 620 1.0% 3 591 82
LURASIDONE 617 3.6% 41 38 2

View all 617 drugs →

Top 3 Drugs Associated With Sedation

2,244 reports
2,130 reports
2,051 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)