Sickle cell disease: Which Medications Cause It? (444 Reports Across 20 Drugs)
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Sickle cell disease has been reported as an adverse event with 20 different drugs in the FDA's FAERS database, with 444 total reports. 29 of these reports resulted in death.The drugs most commonly associated with Sickle cell disease are VOXELOTOR, GLUTAMINE, and DEFERASIROX.
444
Total Reports
20
Drugs Involved
29
Deaths
311
Hospitalizations
35.6 yrs
Average Patient Age
59.3% / 40.7%
Female / Male
Which Drugs Cause Sickle cell disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| VOXELOTOR | 170 | 0.8% | 8 | 130 | 0 |
| GLUTAMINE | 54 | 1.6% | 0 | 47 | 0 |
| DEFERASIROX | 42 | 0.4% | 0 | 33 | 1 |
| AMBRISENTAN | 22 | 0.0% | 1 | 20 | 0 |
| TREPROSTINIL | 21 | 0.0% | 0 | 19 | 0 |
| MACITENTAN | 19 | 0.0% | 3 | 18 | 0 |
| CRIZANLIZUMAB-TMCA | 13 | 1.2% | 2 | 7 | 0 |
| EFAVIRENZ | 13 | 0.2% | 0 | 0 | 0 |
| LAMIVUDINE | 13 | 0.1% | 0 | 0 | 0 |
| LOPINAVIR\RITONAVIR | 13 | 0.2% | 0 | 0 | 0 |
| NELFINAVIR | 13 | 1.1% | 0 | 0 | 0 |
| ZIDOVUDINE | 13 | 0.2% | 0 | 0 | 0 |
| SELEXIPAG | 10 | 0.1% | 1 | 9 | 0 |
| RIOCIGUAT | 8 | 0.0% | 1 | 8 | 0 |
| ABATACEPT | 6 | 0.0% | 0 | 0 | 0 |
| ADALIMUMAB | 6 | 0.0% | 0 | 2 | 0 |
| DEFERIPRONE | 5 | 0.2% | 2 | 4 | 0 |
| DOLUTEGRAVIR | 5 | 0.1% | 0 | 1 | 1 |
| MORPHINE | 5 | 0.0% | 5 | 0 | 0 |
| OXYCODONE | 5 | 0.0% | 4 | 2 | 0 |