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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Skeletal injury: Which Medications Cause It? (9,626 Reports Across 91 Drugs)

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Skeletal injury has been reported as an adverse event with 91 different drugs in the FDA's FAERS database, with 9,626 total reports. 221 of these reports resulted in death.The drugs most commonly associated with Skeletal injury are TENOFOVIR DISOPROXIL, EMTRICITABINE\TENOFOVIR DISOPROXIL, and EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL.

9,626
Total Reports
91
Drugs Involved
221
Deaths
847
Hospitalizations
49.2 yrs
Average Patient Age
33.0% / 67.0%
Female / Male

Which Drugs Cause Skeletal injury Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
TENOFOVIR DISOPROXIL 8,320 30.8% 172 490 0
EMTRICITABINE\TENOFOVIR DISOPROXIL 7,161 18.2% 155 430 0
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL 4,272 23.0% 60 231 0
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL 3,015 35.8% 41 138 0
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL 2,766 38.3% 40 127 0
LOPINAVIR\RITONAVIR 95 1.2% 2 10 0
ADALIMUMAB 86 0.0% 1 35 0
ALENDRONATE 43 0.2% 1 36 0
ZOLEDRONIC ACID 42 0.1% 4 14 4
RIBOCICLIB 34 0.1% 3 7 6
METHOTREXATE 30 0.0% 0 3 1
ETANERCEPT 27 0.0% 0 6 0
FOSAMAX 25 2.6% 0 24 0
TERIPARATIDE 24 0.0% 0 4 0
FULVESTRANT 21 0.1% 5 9 2
PREGABALIN 21 0.0% 1 9 2
TOFACITINIB 20 0.0% 0 6 0
LENALIDOMIDE 19 0.0% 0 4 0
SECUKINUMAB 19 0.0% 0 2 0
PREDNISONE 18 0.0% 0 0 0

View all 91 drugs →

Top 3 Drugs Associated With Skeletal injury

8,320 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)