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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sleep disorder: Which Medications Cause It? (53,264 Reports Across 1,470 Drugs)

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Sleep disorder has been reported as an adverse event with 1,470 different drugs in the FDA's FAERS database, with 53,264 total reports. 2,682 of these reports resulted in death.The drugs most commonly associated with Sleep disorder are DUPILUMAB, METHOTREXATE, and ADALIMUMAB.

53,264
Total Reports
1,470
Drugs Involved
2,682
Deaths
11,062
Hospitalizations
51.8 yrs
Average Patient Age
64.1% / 35.9%
Female / Male

Which Drugs Cause Sleep disorder Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
DUPILUMAB 5,906 1.6% 1 131 0
METHOTREXATE 3,642 1.4% 1,265 1,945 1,451
ADALIMUMAB 3,449 0.7% 1,207 1,801 1,367
ABATACEPT 3,179 2.7% 1,145 1,813 1,430
TOCILIZUMAB 3,167 3.2% 1,275 1,797 1,342
ETANERCEPT 3,072 0.9% 929 1,568 1,101
RITUXIMAB 2,949 1.7% 1,284 1,790 1,433
LEFLUNOMIDE 2,670 4.7% 1,203 1,754 1,406
TOFACITINIB 2,519 1.6% 1,070 1,436 1,223
DICLOFENAC 2,500 2.9% 1,257 1,551 1,421
PREDNISONE 2,452 1.6% 1,194 1,794 1,406
OXYCODONE 2,384 1.3% 1,036 1,381 1,089
HYDROXYCHLOROQUINE 2,358 3.5% 1,136 1,640 1,288
SULFASALAZINE 2,280 5.7% 1,171 1,669 1,318
ACETAMINOPHEN 2,227 1.6% 1,143 1,567 1,335
GOLIMUMAB 2,138 3.1% 1,135 1,458 1,303
CERTOLIZUMAB PEGOL 2,117 2.1% 1,118 1,399 1,263
INFLIXIMAB 2,064 1.5% 1,162 1,566 1,322
SECUKINUMAB 1,928 1.3% 1,171 1,341 1,328
ALENDRONATE 1,921 6.9% 1,207 1,554 1,378

View all 1,470 drugs →

Top 3 Drugs Associated With Sleep disorder

5,906 reports
3,642 reports
3,449 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)