Steroid withdrawal syndrome: Which Medications Cause It? (863 Reports Across 46 Drugs)
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Steroid withdrawal syndrome has been reported as an adverse event with 46 different drugs in the FDA's FAERS database, with 863 total reports. 8 of these reports resulted in death.The drugs most commonly associated with Steroid withdrawal syndrome are HYDROCORTISONE, BETAMETHASONE, and MOMETASONE FUROATE.
863
Total Reports
46
Drugs Involved
8
Deaths
227
Hospitalizations
34.5 yrs
Average Patient Age
69.9% / 30.1%
Female / Male
Which Drugs Cause Steroid withdrawal syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| HYDROCORTISONE | 269 | 1.1% | 1 | 56 | 11 |
| BETAMETHASONE | 150 | 1.9% | 0 | 38 | 13 |
| MOMETASONE FUROATE | 131 | 1.1% | 0 | 30 | 3 |
| PREDNISOLONE | 123 | 0.2% | 0 | 40 | 12 |
| CLOBETASONE | 104 | 33.2% | 0 | 21 | 12 |
| PREDNISONE | 98 | 0.1% | 0 | 26 | 2 |
| CLOBETASOL | 97 | 1.2% | 0 | 27 | 11 |
| TACROLIMUS | 69 | 0.1% | 0 | 16 | 5 |
| TRIAMCINOLONE | 57 | 0.9% | 0 | 9 | 3 |
| DEXAMETHASONE | 51 | 0.0% | 2 | 24 | 6 |
| TRIAMCINOLONE ACETONIDE | 43 | 0.3% | 0 | 7 | 5 |
| BETAMETHASONE DIPROPIONATE | 34 | 1.3% | 0 | 4 | 1 |
| METHYLPREDNISOLONE | 34 | 0.1% | 0 | 13 | 0 |
| MOMETASONE | 26 | 1.5% | 0 | 3 | 0 |
| BUDESONIDE | 24 | 0.1% | 0 | 3 | 0 |
| FLUTICASONE | 24 | 0.1% | 0 | 5 | 4 |
| BETAMETHASONE\FUSIDIC ACID | 21 | 25.3% | 0 | 0 | 0 |
| METHYLPREDNISOLONE ACEPONATE | 20 | 16.5% | 0 | 5 | 0 |
| DESONIDE | 17 | 1.3% | 0 | 0 | 0 |
| HYDROCORTISONE\MICONAZOLE | 12 | 27.3% | 0 | 6 | 0 |