Subcutaneous emphysema: Which Medications Cause It? (675 Reports Across 70 Drugs)
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Subcutaneous emphysema has been reported as an adverse event with 70 different drugs in the FDA's FAERS database, with 675 total reports. 177 of these reports resulted in death.The drugs most commonly associated with Subcutaneous emphysema are PREDNISOLONE, PREDNISONE, and METHYLPREDNISOLONE.
675
Total Reports
70
Drugs Involved
177
Deaths
462
Hospitalizations
52.2 yrs
Average Patient Age
42.2% / 57.8%
Female / Male
Which Drugs Cause Subcutaneous emphysema Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| PREDNISOLONE | 76 | 0.1% | 18 | 53 | 13 |
| PREDNISONE | 53 | 0.0% | 5 | 41 | 19 |
| METHYLPREDNISOLONE | 51 | 0.1% | 16 | 39 | 18 |
| TACROLIMUS | 44 | 0.1% | 8 | 37 | 12 |
| RITUXIMAB | 34 | 0.0% | 9 | 20 | 8 |
| DEXAMETHASONE | 30 | 0.0% | 12 | 20 | 14 |
| MYCOPHENOLATE MOFETIL | 30 | 0.0% | 5 | 25 | 7 |
| METHOTREXATE | 23 | 0.0% | 10 | 11 | 7 |
| CARBON DIOXIDE | 20 | 18.7% | 0 | 3 | 1 |
| REMDESIVIR | 20 | 0.2% | 13 | 7 | 5 |
| IMATINIB | 18 | 0.0% | 7 | 16 | 2 |
| OXYGEN | 18 | 1.0% | 5 | 8 | 3 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 17 | 0.0% | 0 | 15 | 11 |
| NINTEDANIB | 16 | 0.1% | 4 | 10 | 1 |
| CISPLATIN | 15 | 0.0% | 6 | 8 | 3 |
| CYCLOSPORINE | 15 | 0.0% | 11 | 9 | 1 |
| TOCILIZUMAB | 15 | 0.0% | 4 | 10 | 6 |
| CYCLOPHOSPHAMIDE | 14 | 0.0% | 6 | 6 | 6 |
| HYDROCORTISONE | 14 | 0.1% | 0 | 14 | 2 |
| NIVOLUMAB | 14 | 0.0% | 7 | 14 | 3 |