Substance dependence: Which Medications Cause It? (633 Reports Across 56 Drugs)
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Substance dependence has been reported as an adverse event with 56 different drugs in the FDA's FAERS database, with 633 total reports. 71 of these reports resulted in death.The drugs most commonly associated with Substance dependence are OXYCODONE, COCAINE, and MORPHINE.
633
Total Reports
56
Drugs Involved
71
Deaths
123
Hospitalizations
34.4 yrs
Average Patient Age
39.4% / 60.6%
Female / Male
Which Drugs Cause Substance dependence Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| OXYCODONE | 256 | 0.1% | 40 | 24 | 2 |
| COCAINE | 168 | 1.2% | 22 | 21 | 1 |
| MORPHINE | 163 | 0.1% | 24 | 11 | 1 |
| DIAMORPHINE | 126 | 1.4% | 15 | 12 | 0 |
| HYDROMORPHONE | 123 | 0.2% | 24 | 13 | 0 |
| CANNABIS SATIVA SUBSP. INDICA TOP | 96 | 1.1% | 10 | 9 | 0 |
| FENTANYL | 91 | 0.1% | 33 | 1 | 0 |
| ALCOHOL | 85 | 0.4% | 11 | 10 | 0 |
| METHAMPHETAMINE | 83 | 1.0% | 9 | 10 | 0 |
| ALPRAZOLAM | 75 | 0.2% | 21 | 17 | 5 |
| ACETAMINOPHEN\OXYCODONE | 53 | 0.1% | 10 | 13 | 0 |
| DIACETYLMORPHINE | 48 | 2.2% | 5 | 1 | 1 |
| METHADONE | 44 | 0.2% | 14 | 9 | 1 |
| ARIPIPRAZOLE | 36 | 0.1% | 0 | 18 | 0 |
| TRAMADOL | 35 | 0.1% | 1 | 6 | 1 |
| ACETAMINOPHEN\OXYCODONE\OXYCODONE TEREPHTHALATE | 33 | 0.3% | 7 | 2 | 0 |
| BUPRENORPHINE | 33 | 0.0% | 5 | 21 | 1 |
| CODEINE | 29 | 0.1% | 3 | 0 | 1 |
| QUETIAPINE | 29 | 0.0% | 1 | 14 | 7 |
| ACETAMINOPHEN\HYDROCODONE | 25 | 0.0% | 1 | 3 | 0 |