Substance use: Which Medications Cause It? (1,388 Reports Across 133 Drugs)
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Substance use has been reported as an adverse event with 133 different drugs in the FDA's FAERS database, with 1,388 total reports. 135 of these reports resulted in death.The drugs most commonly associated with Substance use are COCAINE, SODIUM OXYBATE, and METHADONE.
1,388
Total Reports
133
Drugs Involved
135
Deaths
514
Hospitalizations
35.4 yrs
Average Patient Age
38.5% / 61.5%
Female / Male
Which Drugs Cause Substance use Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| COCAINE | 142 | 1.0% | 14 | 87 | 17 |
| SODIUM OXYBATE | 136 | 0.2% | 2 | 24 | 0 |
| METHADONE | 111 | 0.4% | 40 | 38 | 1 |
| CANNABIS SATIVA SUBSP. INDICA TOP | 109 | 1.3% | 9 | 41 | 4 |
| PREGABALIN | 100 | 0.1% | 41 | 32 | 29 |
| FENTANYL | 92 | 0.1% | 21 | 44 | 10 |
| METHAMPHETAMINE | 83 | 1.0% | 16 | 48 | 0 |
| NALTREXONE | 83 | 0.3% | 1 | 5 | 2 |
| ARIPIPRAZOLE | 82 | 0.1% | 2 | 51 | 1 |
| MORPHINE | 72 | 0.1% | 14 | 37 | 0 |
| ALPRAZOLAM | 51 | 0.1% | 12 | 15 | 0 |
| DIAZEPAM | 50 | 0.1% | 11 | 23 | 19 |
| HERBALS\MITRAGYNINE | 50 | 4.6% | 19 | 7 | 6 |
| QUETIAPINE | 49 | 0.1% | 22 | 17 | 2 |
| BUPRENORPHINE | 47 | 0.1% | 1 | 18 | 12 |
| NITROUS | 47 | 4.5% | 3 | 20 | 11 |
| TRAZODONE | 46 | 0.2% | 9 | 35 | 0 |
| METFORMIN | 43 | 0.1% | 0 | 41 | 1 |
| CLONAZEPAM | 41 | 0.1% | 1 | 23 | 16 |
| DIVALPROEX | 41 | 0.4% | 0 | 37 | 0 |