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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sudden death: Which Medications Cause It? (5,600 Reports Across 483 Drugs)

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Sudden death has been reported as an adverse event with 483 different drugs in the FDA's FAERS database, with 5,600 total reports. 5,577 of these reports resulted in death.The drugs most commonly associated with Sudden death are CLOZAPINE, NIVOLUMAB, and SACUBITRIL\VALSARTAN.

5,600
Total Reports
483
Drugs Involved
5,577
Deaths
601
Hospitalizations
59.6 yrs
Average Patient Age
37.5% / 62.5%
Female / Male

Which Drugs Cause Sudden death Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
CLOZAPINE 173 0.2% 173 31 2
NIVOLUMAB 164 0.2% 164 41 8
SACUBITRIL\VALSARTAN 160 0.1% 160 17 5
DEXAMETHASONE 150 0.1% 149 9 3
ACETAMINOPHEN 149 0.1% 149 14 8
OLANZAPINE 144 0.3% 144 9 19
DIAZEPAM 125 0.3% 125 5 7
IBRUTINIB 124 0.2% 123 9 3
RISPERIDONE 113 0.1% 113 17 11
ARIPIPRAZOLE 110 0.2% 110 12 5
QUETIAPINE 109 0.2% 109 7 13
LENALIDOMIDE 106 0.0% 106 9 2
FUROSEMIDE 103 0.2% 102 9 2
APIXABAN 101 0.1% 100 8 7
BEVACIZUMAB 97 0.1% 97 4 2
RIVAROXABAN 93 0.1% 93 10 4
ALPRAZOLAM 89 0.2% 89 3 6
PEMBROLIZUMAB 89 0.1% 89 16 3
ESOMEPRAZOLE 83 0.1% 83 4 3
MIRTAZAPINE 83 0.3% 82 12 1

View all 483 drugs →

Top 3 Drugs Associated With Sudden death

173 reports
164 reports
160 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)