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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Tendon rupture: Which Medications Cause It? (7,778 Reports Across 317 Drugs)

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Tendon rupture has been reported as an adverse event with 317 different drugs in the FDA's FAERS database, with 7,778 total reports. 88 of these reports resulted in death.The drugs most commonly associated with Tendon rupture are LEVOFLOXACIN, ADALIMUMAB, and CIPROFLOXACIN.

7,778
Total Reports
317
Drugs Involved
88
Deaths
2,539
Hospitalizations
60.2 yrs
Average Patient Age
55.0% / 45.0%
Female / Male

Which Drugs Cause Tendon rupture Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
LEVOFLOXACIN 1,321 3.3% 18 387 30
ADALIMUMAB 1,124 0.2% 2 304 5
CIPROFLOXACIN 880 2.0% 1 288 32
ETANERCEPT 257 0.1% 0 75 1
SIMVASTATIN 252 0.9% 0 121 10
PREDNISONE 239 0.2% 2 91 2
METHOTREXATE 238 0.1% 0 113 0
ATORVASTATIN 205 0.3% 0 75 8
UPADACITINIB 178 0.3% 0 39 0
TOFACITINIB 169 0.1% 1 58 0
PREDNISOLONE 150 0.2% 23 59 21
RITUXIMAB 114 0.1% 1 65 0
ROSUVASTATIN 114 0.3% 0 32 0
TOCILIZUMAB 112 0.1% 1 76 0
ABATACEPT 109 0.1% 0 60 0
RISANKIZUMAB-RZAA 108 0.2% 0 19 0
SECUKINUMAB 94 0.1% 1 44 3
MOXIFLOXACIN 91 0.6% 0 37 0
METHYLPREDNISOLONE 86 0.1% 0 40 1
INFLIXIMAB 76 0.1% 0 26 1

View all 317 drugs →

Top 3 Drugs Associated With Tendon rupture

1,321 reports
1,124 reports
880 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)