Teratogenicity: Which Medications Cause It? (228 Reports Across 33 Drugs)
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Teratogenicity has been reported as an adverse event with 33 different drugs in the FDA's FAERS database, with 228 total reports. 12 of these reports resulted in death.The drugs most commonly associated with Teratogenicity are LEVETIRACETAM, DOLUTEGRAVIR, and LEUCOVORIN.
228
Total Reports
33
Drugs Involved
12
Deaths
35
Hospitalizations
15.5 yrs
Average Patient Age
61.3% / 38.7%
Female / Male
Which Drugs Cause Teratogenicity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LEVETIRACETAM | 39 | 0.1% | 0 | 0 | 0 |
| DOLUTEGRAVIR | 36 | 0.3% | 0 | 21 | 21 |
| LEUCOVORIN | 36 | 0.1% | 0 | 21 | 21 |
| METHYLDOPA | 36 | 1.4% | 0 | 21 | 21 |
| SULFAMETHOXAZOLE\TRIMETHOPRIM | 36 | 0.1% | 0 | 21 | 21 |
| PREDNISONE | 34 | 0.0% | 0 | 21 | 21 |
| VALGANCICLOVIR | 32 | 0.4% | 0 | 21 | 21 |
| RITONAVIR | 28 | 0.2% | 0 | 12 | 12 |
| EMTRICITABINE\TENOFOVIR DISOPROXIL | 27 | 0.1% | 0 | 13 | 13 |
| OMEPRAZOLE | 21 | 0.0% | 0 | 20 | 20 |
| SERTRALINE | 20 | 0.0% | 1 | 0 | 0 |
| DARUNAVIR ETHANOLATE | 18 | 0.4% | 0 | 3 | 3 |
| PREDNISOLONE | 16 | 0.0% | 2 | 4 | 3 |
| VALPROATE | 16 | 0.1% | 0 | 0 | 0 |
| DARUNAVIR\RITONAVIR | 15 | 2.2% | 0 | 15 | 15 |
| CARBAMAZEPINE | 13 | 0.1% | 0 | 0 | 0 |
| LAMOTRIGINE | 13 | 0.0% | 0 | 0 | 0 |
| DARUNAVIR | 12 | 0.3% | 0 | 11 | 11 |
| OLANZAPINE | 12 | 0.0% | 0 | 1 | 1 |
| MYCOPHENOLATE MOFETIL | 11 | 0.0% | 1 | 4 | 3 |