Terminal state: Which Medications Cause It? (5,423 Reports Across 195 Drugs)
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Terminal state has been reported as an adverse event with 195 different drugs in the FDA's FAERS database, with 5,423 total reports. 1,352 of these reports resulted in death.The drugs most commonly associated with Terminal state are LEUPROLIDE, DENOSUMAB, and DARBEPOETIN ALFA.
5,423
Total Reports
195
Drugs Involved
1,352
Deaths
1,801
Hospitalizations
68.4 yrs
Average Patient Age
41.6% / 58.4%
Female / Male
Which Drugs Cause Terminal state Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| LEUPROLIDE | 700 | 1.0% | 125 | 134 | 76 |
| DENOSUMAB | 563 | 0.4% | 48 | 121 | 21 |
| DARBEPOETIN ALFA | 299 | 0.9% | 62 | 96 | 17 |
| CARBIDOPA\LEVODOPA | 289 | 0.5% | 162 | 97 | 113 |
| ADALIMUMAB | 253 | 0.1% | 79 | 165 | 128 |
| OCTREOTIDE | 232 | 1.0% | 96 | 104 | 55 |
| ETANERCEPT | 200 | 0.1% | 72 | 132 | 115 |
| RITUXIMAB | 182 | 0.1% | 73 | 128 | 118 |
| ABATACEPT | 181 | 0.2% | 71 | 129 | 118 |
| CLOZAPINE | 180 | 0.2% | 90 | 70 | 27 |
| TOCILIZUMAB | 179 | 0.2% | 74 | 126 | 118 |
| INFLIXIMAB | 177 | 0.1% | 70 | 125 | 115 |
| METHOTREXATE | 177 | 0.1% | 68 | 123 | 111 |
| ZOLEDRONIC ACID | 177 | 0.5% | 28 | 25 | 13 |
| LEFLUNOMIDE | 172 | 0.3% | 70 | 124 | 114 |
| SULFASALAZINE | 172 | 0.4% | 70 | 124 | 114 |
| HYDROXYCHLOROQUINE | 171 | 0.3% | 70 | 123 | 113 |
| PIMAVANSERIN | 168 | 0.4% | 50 | 46 | 6 |
| ANAKINRA | 149 | 1.2% | 54 | 124 | 114 |
| GOLD THIOMALATE | 142 | 3.2% | 70 | 95 | 114 |